1-(5-(Trifluoromethoxy)-1H-indol-3-yl)ethan-1-one CAS 1386456-79-6
| CAS No. | 1386456-79-6 |
| Molecular Formula | C11H8F3NO2 |
| Molecular Weight | 243.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(5-(Trifluoromethoxy)-1H-indol-3-yl)ethan-1-one (CAS 1386456-79-6), molecular formula C11H8F3NO2 and molecular weight 243.18 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C11H8F3NO2, 1-(5-(Trifluoromethoxy)-1H-indol-3-yl)ethan-1-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 243.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8F3NO2 |
| Molecular Weight | 243.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 6-METHOXY-3-(TRIFLUOROMETHYL)QUINOLIN-2(1H)-ONE (CAS 1371589-18-2)
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- Methyl 7-(trifluoromethyl)-1H-indole-2-carboxylate (CAS 1362860-90-9)
- 1-(2,2,2-Trifluoroethyl)-1H-indole-3-carboxylic acid (CAS 1411719-35-1)
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- 3-(m-Tolyl)-1-(o-tolyl)-1H-pyrazol-5-amine (CAS 618098-38-7)
- BMS-265246 (CAS 582315-72-8)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
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