4-(4-(Trifluoromethoxy)phenyl)-1,2,3,6-tetrahydropyridine CAS 681484-40-2

Description

Compared with other compounds in its class, the molecular weight of 243.22 g/mol gives 4-(4-(Trifluoromethoxy)phenyl)-1,2,3,6-tetrahydropyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 4-(4-(Trifluoromethoxy)phenyl)-1,2,3,6-tetrahydropyridine (CAS 681484-40-2), a certified reference material (molecular formula C12H12F3NO, MW 243.22 g/mol) for analytical method development and quality control.

The molecular framework of 4-(4-(Trifluoromethoxy)phenyl)-1,2,3,6-tetrahydropyridine (C12H12F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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