1-[5-Chloro-6-(2-methylpropoxy)-3-pyridinyl]-3-methyl-N-(methylsulfonyl)-1H-indazole-5-carboxamide CAS 1387633-03-5
| CAS No. | 1387633-03-5 |
| Molecular Formula | C19H21ClN4O4S |
| Molecular Weight | 436.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-[5-Chloro-6-(2-methylpropoxy)-3-pyridinyl]-3-methyl-N-(methylsulfonyl)-1H-indazole-5-carboxamide (CAS 1387633-03-5), a certified reference material (molecular formula C19H21ClN4O4S, MW 436.91 g/mol) for analytical method development and quality control.
1-[5-Chloro-6-(2-methylpropoxy)-3-pyridinyl]-3-methyl-N-(methylsulfonyl)-1H-indazole-5-carboxamide (C19H21ClN4O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-[5-Chloro-6-(2-methylpropoxy)-3-pyridinyl]-3-methyl-N-(methylsulfonyl)-1H-indazole-5-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H21ClN4O4S |
| Molecular Weight | 436.91 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- N-(5-Chloro-2-methoxyphenyl)-2-((4-cyano-3-methylbenzo[4,5]imidazo[1,2-a]pyridin-1-yl)thio)acetamide (CAS 868357-74-8)
- 4-(2-Chloro-phenyl)-5-[3-(morpholine-4-sulfonyl)-phenyl]-4H-[1,2,4]triazole-3-thiol (CAS 748793-42-2)
- 2-Chloro-N-((3S,4S)-4-hydroxy-1-tosylpyrrolidin-3-yl)-N-((R)-1-phenylethyl)acetamide (CAS 1159908-19-6)
- 1-(3-Chloro-4-fluorophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 1796900-09-8)
- 3-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-1-(4-methoxybenzoyl)-1H-pyrazole (CAS 477711-01-6)
- 3-(2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-ylidene)hydrazinyl)quinoxalin-2(1H)-one (CAS 338412-85-4)
- (E)-[(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methylidene][(3-methoxyphenyl)methoxy]amine (CAS 1092343-82-2)
- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenyl N-(4-methoxyphenyl)carbamate (CAS 338750-30-4)
Recommended Standards
- Fluocinolone Acetonide Impurity 46 (CAS CATO-C4X-238146)
- (2E)-N'-[(1E)-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}methylidene]-3-(2,5-dimethylphenyl)prop-2-enehydrazide (CAS 677749-46-1)
- Ochratoxin C-d5 (CAS 1356840-94-2)
- 3-(4-Chlorophenyl)-5-((4-nitrobenzyl)thio)-4-(p-tolyl)-4H-1,2,4-triazole (CAS 477330-92-0)
- Benzyl 1H-indole-1-carboxylate (CAS 109241-98-7)
- 4,5-Dichloro-1,6-dimethyl-1H-indole-2-carboxylic acid (CAS 2244454-05-3)
- 5-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoxazole (CAS 1352734-32-7)
- trans-3-Morpholinocyclobutan-1-amine (CAS 2839511-99-6)
- 4,6-Dimethyl-2-nitroaniline (CAS 1635-84-3)
- 3-Iodo-N-((1-methyl-1h-pyrazol-4-yl)methyl)aniline (CAS 1152555-91-3)
- (R)-1-(Pyridin-3-yl)pyrrolidin-3-amine (CAS 309959-34-0)
- 2-(Bis(4-chlorophenyl)methyl)-2H-benzo[d][1,2,3]triazole (CAS 132870-26-9)
- 3-Chloro-4-hydroxyquinoline (CAS 58550-89-3)
- Peptide 431 (CAS CATO-CPTD788431)
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