3-(2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-ylidene)hydrazinyl)quinoxalin-2(1H)-one CAS 338412-85-4
| CAS No. | 338412-85-4 |
| Molecular Formula | C19H16ClF3N6O |
| Molecular Weight | 436.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-ylidene)hydrazinyl)quinoxalin-2(1H)-one (CAS 338412-85-4), molecular formula C19H16ClF3N6O and molecular weight 436.82 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-ylidene)hydrazinyl)quinoxalin-2(1H)-one (C19H16ClF3N6O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H16ClF3N6O |
| Molecular Weight | 436.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 6 |
Related Chloro Standards
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Recommended Standards
- (5-((2-Chlorobenzyl)sulfonyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl cyclopropanecarboxylate (CAS 955964-19-9)
- 2-((2-((Chloromethyl)sulfonyl)-5-(trifluoromethyl)phenyl)amino)-N-(4-methoxyphenyl)acetamide (CAS 431939-05-8)
- 2-Methyltriacontane (CAS 1560-72-1)
- Triacontanal (CAS 22725-63-9)
- pyrido[2,3-b][1,5]benzoxazepin-5(6H)-one (CAS 10189-46-5)
- 2-(Aminomethyl)-5-(difluoromethyl)-4-(trifluoromethoxy)pyridine-3-methanol (CAS 1806760-43-9)
- (2R,3S)-3-Hydroxynorleucine (CAS 59286-25-8)
- 3-(aminomethyl)-1-benzylpyrrolidin-3-amine trihydrochloride (CAS 1803595-07-4)
- N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-(4-aminophenyl)acetamide (CAS 794465-78-4)
- 1-(4-Chlorophenyl)-2-((5-(hydroxymethyl)-1-methyl-1H-imidazol-2-yl)thio)ethan-1-one (CAS 338422-49-4)
- Tert-butyl 2-vinylpiperidine-1-carboxylate (CAS 176324-61-1)
- trans-4-Phenyl-cyclohexylamine hydrochloride (CAS 5769-08-4)
- 2-Methylbutyric Acid-Methyl Ester (CAS 868-57-5)
- Pheromone Biosynthesis Activating Neuropeptide (Helicoverpa assulta, Heliothis zea) (CAS 122071-54-9)
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