8-Bromo-2,4-dichloro-6-methoxyquinazoline CAS 1388026-74-1

Description

The occurrence of 8-Bromo-2,4-dichloro-6-methoxyquinazoline is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 8-Bromo-2,4-dichloro-6-methoxyquinazoline (CAS 1388026-74-1), a certified reference material (molecular formula C9H5BrCl2N2O, MW 307.96 g/mol) for analytical method development and quality control.

The molecular framework of 8-Bromo-2,4-dichloro-6-methoxyquinazoline (C9H5BrCl2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 8-Bromo-2,4-dichloro-6-methoxyquinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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