6-Bromo-2,4-dichloro-8-methoxyquinazoline CAS 864292-36-4
| CAS No. | 864292-36-4 |
| Molecular Formula | C9H5BrCl2N2O |
| Molecular Weight | 307.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Bromo-2,4-dichloro-8-methoxyquinazoline is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 6-Bromo-2,4-dichloro-8-methoxyquinazoline (CAS 864292-36-4), a certified reference material (molecular formula C9H5BrCl2N2O, MW 307.96 g/mol) for analytical method development and quality control.
The molecular framework of 6-Bromo-2,4-dichloro-8-methoxyquinazoline (C9H5BrCl2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Bromo-2,4-dichloro-8-methoxyquinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5BrCl2N2O |
| Molecular Weight | 307.96 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 6-Bromo-2,5-dichloro-8-methoxyquinazoline (CAS 1036755-87-9)
- 8-Bromo-2,4-dichloro-6-methoxyquinazoline (CAS 1388026-74-1)
- 5-Bromo-2,4-dichloro-8-methoxyquinazoline (CAS 1594537-70-8)
- 5-Bromo-2-(2,5-dichlorophenyl)-2H-1,2,3-triazol-4-amine (CAS 1779134-52-9)
- 3-Bromo-6-chloro-2-(chloromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 87779-06-4)
- 7-Bromo-2,5-dichloro-8-methoxyquinazoline (CAS 953039-88-8)
- 2-Bromo-5-chloro-4-fluorobenzenesulfonyl chloride (CAS 1019018-84-8)
- 5-Bromo-4-chloro-2-fluoro-benzenesulfonyl chloride (CAS 1070972-67-6)
Recommended Standards
- 2-[(E)-4-iodobut-1-enyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2753097-31-1)
- Methyl 3,5-dibromo-2-methylbenzoate (CAS 1000342-33-5)
- (S)-6,8-Dibromochroman-4-ol (CAS 1015224-07-3)
- 1,6-Dibromodulcitol (CAS 10318-26-0)
- 3-(4-Fluorophenyl)-5,6-dimethyl-2-sulfanylthieno[2,3-d]pyrimidin-4(3h)-one (CAS 588711-33-5)
- (1R,2R)-2-Hydroxycyclopentyl acetate (CAS 105663-22-7)
- 5-Bromo-2-(2,4-dimethylphenoxy)aniline (CAS 946700-10-3)
- 3-methyl-5-(2-phenoxyacetamido)thiophene-2-carboxylic acid (CAS 1016535-37-7)
- N-Benzyl-1H-pyrrolo[2,3-b]pyridine-5-carboxamide (CAS 858116-65-1)
- 3-(Methoxymethyl)picolinonitrile (CAS 863548-34-9)
- MS 245 Oxalate (CAS 275363-58-1)
- 3-Cyclopropylprop-2-yn-1-ol (CAS 101974-69-0)
- 7-Methoxyoxepino[3,2-d]isoxazole (CAS 133708-06-2)
- Glucagon Monohydrochloride (CAS 28270-04-4)
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