5-Bromo-7-[trans-4-(tert-butyldimethylsilanyloxy)cyclohexyl]-2-chloro-7H-pyrrolo[2,3-d]pyrimidine CAS 1392804-15-7
| CAS No. | 1392804-15-7 |
| Molecular Formula | C18H27BrClN3OSi |
| Molecular Weight | 444.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Bromo-7-[trans-4-(tert-butyldimethylsilanyloxy)cyclohexyl]-2-chloro-7H-pyrrolo[2,3-d]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-Bromo-7-[trans-4-(tert-butyldimethylsilanyloxy)cyclohexyl]-2-chloro-7H-pyrrolo[2,3-d]pyrimidine (CAS 1392804-15-7), molecular formula C18H27BrClN3OSi and molecular weight 444.87 g/mol, is a CATO reference standard with documented purity and traceability.
5-Bromo-7-[trans-4-(tert-butyldimethylsilanyloxy)cyclohexyl]-2-chloro-7H-pyrrolo[2,3-d]pyrimidine (C18H27BrClN3OSi) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H27BrClN3OSi |
| Molecular Weight | 444.87 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
- 7-Bromo-4,6-dichloro-8-fluoro-1,2-dihydroquinolin-2-yl trifluoromethanesulfonate (CAS 2857930-14-2)
- 1,2-Bis(5-bromo-2-chlorophenyl)disulfane (CAS 792952-65-9)
- 4-Bromo-5-methyl-3-(1,2,2,2-tetrafluoro-1-(perfluoropropoxy)ethyl)-1H-pyrazole (CAS 231630-82-3)
- 4-Bromo-2-(3-iodophenyl)-6-methoxy-2H-benzo[d][1,2,3]triazol-5-amine (CAS 1706442-98-9)
- 5-Bromo-N-(2-(2-(4-(trifluoromethyl)phenyl)thiazol-4-yl)ethyl)furan-2-carboxamide (CAS 896679-30-4)
- 3-Bromo-8-chloro-2-(3,4-dichlorophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 866137-88-4)
- 6-Bromo-3-fluoro-N,N-bis(4-methoxybenzyl)-4-methylpyridin-2-amine (CAS 2803281-45-8)
- 5-bromo-1-methyl-3-[[5-[(2R)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]-2-pyridyl]amino]pyridin-2-one (CAS 1433860-44-6)
Recommended Standards
- Lemborexant Impurity 27 (CAS CATO-C4X-304227)
- Iridium, trichloro[1,1'-thiobis[butane]]- (CAS 67953-74-6)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-5,6-diphenyl-1,2,4-triazine (CAS 866133-97-3)
- 2-{[2-(5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}thiophen-2-yl)-2-oxoethyl]sulfanyl}pyridin-1-ium-1-olate (CAS 339016-51-2)
- (R)-Isoindoline-1-carboxylic Acid (CAS 1388796-96-0)
- 2-(4-Amino-2,6-dimethylphenoxy)-1-(pyrrolidin-1-yl)ethan-1-one (CAS 893766-09-1)
- 3-(1H-1,2,4-Triazol-1-yl)-5-(trifluoromethyl)picolinonitrile (CAS 1823182-93-9)
- (4AR,6S,7R,8S,8aR)-8-(allyloxy)-6-(ethylthio)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl 4-oxopentanoate (CAS 1186583-16-3)
- (S)-3-methyl-2-oxooxazolidine-5-carboxylic acid (CAS 107717-00-0)
- 1-{4H,5H,6H-pyrrolo[1,2-b]pyrazol-3-yl}ethan-1-one (CAS 1909306-04-2)
- 2,4,6-Triphenyl-1,3,5-triazine (CAS 493-77-6)
- 2,2-Difluoro-2-Nitro-1-Phenylethanone (CAS 33128-13-1)
- 3-(2H-Chromen-3-yl)-1,2,4-oxadiazole-5-carboxylic acid (CAS 1269534-55-5)
- D-Ile27-Tirzepatide (CAS CATO-CPTD788907)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com