B-[4-(Trifluoromethoxy)phenyl]boronic Acid CAS 139301-27-2
| CAS No. | 139301-27-2 |
| Molecular Formula | C7H6BF3O3 |
| Molecular Weight | 205.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of B-[4-(Trifluoromethoxy)phenyl]boronic Acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies B-[4-(Trifluoromethoxy)phenyl]boronic Acid (CAS 139301-27-2), a certified reference material (molecular formula C7H6BF3O3, MW 205.93 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, B-[4-(Trifluoromethoxy)phenyl]boronic Acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 205.93 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures B-[4-(Trifluoromethoxy)phenyl]boronic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6BF3O3 |
| Molecular Weight | 205.93 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
Related B Standards
- 2-(Trifluoromethoxy)phenylboronic Acid (CAS 175676-65-0)
- (3-(Trifluoromethoxy)phenyl)boronic acid (CAS 179113-90-7)
- 2-(Trifluoromethoxy)benzoic acid (CAS 150436-84-3)
- 2-(Trifluoromethoxy)benzoic Acid (CAS 1979-29-9)
- 4-(Trifluoromethoxy)benzoic Acid (CAS 330-12-1)
- 5-(Trifluoromethoxy)salicylaldehyde (CAS 93249-62-8)
- (1s)-1-[4-(trifluoromethoxy)phenyl]ethan-1-ol (CAS 1108723-47-2)
- 1-Phenyl-2-(trifluoromethoxy)ethan-1-ol (CAS 1171146-29-4)
Recommended Standards
- 3-Amino-2-(trifluoromethyl)pyridine-4-boronic acid (CAS 1228898-11-0)
- (6-Amino-5-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 1189126-37-1)
- 4-Hydroxy-3-(trifluoromethyl)phenylboronic Acid (CAS 1187874-94-7)
- (2-(Difluoromethoxy)-5-fluorophenyl)boronic acid (CAS 958451-71-3)
- BI-224436, >98% (HPLC) (CAS 1155419-89-8)
- Sodium pyrimidine-2-carboxylate (CAS 562101-38-6)
- 5-ethynyl-4-fluoro-1,2-dimethyl-benzimidazole (CAS 2750712-18-4)
- 1-Methyl-4-nitro-1H-pyrazole-5-carboxamide (CAS 92534-72-0)
- 8-fluoro-2-methylquinoline-3-carboxylic acid hydrochloride (CAS 1803599-81-6)
- 3,3-Difluoro-4-Isopropyldihydro-2(3H)-Furanone (CAS 220432-35-9)
- 5-Chloro-2-(cyclohexyloxy)aniline (CAS 893751-21-8)
- Nortriptyline EP Impurity J (CAS 4317-14-0)
- N-Methylpyrrole-d4 (ring-d4) (CAS 190386-37-9)
- [2-31]-Semaglutide C (x TFA Salt) (CAS CATO-C4X-2226118)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com