tert-Butyl 4-[(3,4-difluorophenyl)methyl]piperazine-1-carboxylate CAS 1393441-76-3
| CAS No. | 1393441-76-3 |
| Molecular Formula | C16H22F2N2O2 |
| Molecular Weight | 312.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of tert-Butyl 4-[(3,4-difluorophenyl)methyl]piperazine-1-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
tert-Butyl 4-[(3,4-difluorophenyl)methyl]piperazine-1-carboxylate (CAS 1393441-76-3) is a high-purity analytical reference standard with the molecular formula C16H22F2N2O2 and a molecular weight of 312.35 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, tert-Butyl 4-[(3,4-difluorophenyl)methyl]piperazine-1-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 312.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), tert-Butyl 4-[(3,4-difluorophenyl)methyl]piperazine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H22F2N2O2 |
| Molecular Weight | 312.35 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl 3-amino-4-(3-(difluoromethyl)phenyl)pyrrolidine-1-carboxylate (CAS 1366879-14-2)
- tert-Butyl 4-[(2,6-difluorophenyl)methyl]piperazine-1-carboxylate (CAS 1393442-57-3)
- 2-((6-(1H-Imidazol-1-yl)pyridazin-3-yl)thio)-N-(pyridin-3-yl)acetamide (CAS 1334370-91-0)
- Pyridin-3-yl(3-(3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl)azetidin-1-yl)methanone (CAS 1396749-75-9)
- Ethyl 6-formylchromane-3-carboxylate (CAS 2280844-68-8)
- 2-(Aminomethyl)-3-(difluoromethyl)-5-methylpyridine-4-carboxaldehyde (CAS 1805072-53-0)
- Tert-butyl (3R,4S)-3,4-difluoropyrrolidine-1-carboxylate (CAS 932034-24-7)
- 6,8-dibromoquinazoline-2,4(1H,3H)-dione (CAS 643-37-8)
- Ethyl 2-((4-chlorophenyl)sulfinyl)acetate (CAS 91077-12-2)
- 4-(Chloromethyl)-2-(1,3-dioxolan-2-yl)pyridine (CAS 1256824-16-4)
- Penduletin (CAS 569-80-2)
- (4-Isothiocyanatophenyl)methanamine (CAS 1262139-17-2)
- [4-(4-Methoxyphenyl)piperazin-1-yl]-(2-piperidyl)methanone (CAS 1325303-18-1)
- Neuroendocrine Regulatory Peptide-1 (human) (H-6622.1000) (CAS 954420-50-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com