6,8-dibromoquinazoline-2,4(1H,3H)-dione CAS 643-37-8
| CAS No. | 643-37-8 |
| Molecular Formula | C8H4Br2N2O2 |
| Molecular Weight | 319.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6,8-dibromoquinazoline-2,4(1H,3H)-dione.
6,8-dibromoquinazoline-2,4(1H,3H)-dione (CAS 643-37-8) is a high-purity analytical reference standard with the molecular formula C8H4Br2N2O2 and a molecular weight of 319.94 g/mol.
Structurally, 6,8-dibromoquinazoline-2,4(1H,3H)-dione (C8H4Br2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 319.94 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6,8-dibromoquinazoline-2,4(1H,3H)-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4Br2N2O2 |
| Molecular Weight | 319.94 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related dibromoquinazoline Standards
Recommended Standards
- 6,8-Dibromoimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 904805-36-3)
- 7-Bromo-2,4-dichloro-6-fluoroquinoline-3-carbonitrile (CAS 2788906-57-8)
- 6,8-Dibromoimidazo[1,2-a]pyrazine-2-carboxamide (CAS 87597-29-3)
- Crisaborole impurity 118 (CAS CATO-C4X-2021118)
- 5-Methylfuran-2-boronic Acid Pinacol Ester (CAS 338998-93-9)
- 6-Cyano-3-(difluoromethyl)-5-methylpicolinic acid (CAS 1804422-80-7)
- 1-2-3-4-6-Penta-O-acetyl-5-thio-α-D-glucopyranose (CAS 10227-18-6)
- (E)-[1-(4-Methyl-2-phenyl-1,3-thiazol-5-yl)ethylidene]amino N-(4-methylphenyl)carbamate (CAS 860649-91-8)
- 2-Bromo-1-(3-iodophenyl)ethan-1-one (CAS 61858-38-6)
- 2-Amino-4-(4-chlorophenyl)thiazolo[4,5-d]pyrimidine-5,7(4H,6H)-dione (CAS 898131-77-6)
- 1,1'-(Ethyne-1,2-diylbis(4,1-phenylene))bis(ethan-1-one) (CAS 29619-42-9)
- 3-Bromo-5-cyclopropylpyrazin-2-amine (CAS 1310893-41-4)
- 3,6-Dimethyl-2-phenyl-1H-pyrrolo[3,2-c]pyridin-4(5H)-one (CAS 61191-34-2)
- Tau Peptide (268-282) trifluoroacetate salt (CAS 330456-37-6)
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