3,3-difluoro-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one CAS 1393532-39-2
| CAS No. | 1393532-39-2 |
| Molecular Formula | C7H10F2N2O |
| Molecular Weight | 176.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3,3-difluoro-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one (C7H10F2N2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
3,3-difluoro-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one (CAS 1393532-39-2), molecular formula C7H10F2N2O and molecular weight 176.16 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3,3-difluoro-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H10F2N2O |
| Molecular Weight | 176.16 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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- 2-(1H-Pyrazol-5-yl)pyridine (CAS 192777-54-1)
- Ethyl 4-(2-chlorobenzyl)-3-methyl-4H-benzo[b][1,4]thiazine-2-carboxylate (CAS 339098-19-0)
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