6-Hydroxy-4-nitropicolinic acid CAS 1393572-16-1
| CAS No. | 1393572-16-1 |
| Molecular Formula | C6H4N2O5 |
| Molecular Weight | 184.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Hydroxy-4-nitropicolinic acid is closely related to a carbohydrate-derived structure, an amide group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-Hydroxy-4-nitropicolinic acid (CAS 1393572-16-1), molecular formula C6H4N2O5 and molecular weight 184.11 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 6-Hydroxy-4-nitropicolinic acid (C6H4N2O5) contains a carbohydrate-derived structure, an amide group. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 184.11 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Hydroxy-4-nitropicolinic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4N2O5 |
| Molecular Weight | 184.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Hydroxy Standards
- 3-Hydroxy-3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 1163729-49-4)
- 6-Hydroxy-5-nitropicolinic acid (CAS 1595036-59-1)
- cis-3-hydroxy-3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 1690177-86-6)
- (R)-4-hydroxy-4-(trifluoromethyl)tetrahydro-2H-pyran-2-one (CAS 956398-59-7)
- (s)-4-Hydroxy-4-(trifluoromethyl)tetrahydro-2h-pyran-2-one (CAS 956398-58-6)
- 3-Hydroxy-3-(trifluoromethyl)tetrahydro-4H-pyran-4-one (CAS 693245-82-8)
- 4-Hydroxy-4-(trifluoromethyl)tetrahydro-2H-pyran-2-one (CAS 83191-83-7)
- 4-Hydroxy-5-nitronicotinic acid (CAS 911461-03-5)
Recommended Standards
- N,N'-([1,2,5]Oxadiazolo[3,4-b]pyrazine-5,6-diyl)bis(hydroxylamine) (CAS 132029-06-2)
- 1-((Trifluoromethoxy)methyl)cyclopropane-1-carboxylic acid (CAS 1408279-84-4)
- 4-(2,2,2-trifluoroethoxy)but-2-enoic acid (CAS 1251452-36-4)
- 2-Carboxy-4-nitropyridine 1-oxide (CAS 14933-78-9)
- 2-Chloro-5-ethynyl-1,3-thiazole (CAS 1909337-22-9)
- Ac-Ala-Ala-Ser(PO3H2)-Pro-Arg-pNA trifluoroacetate salt (CAS 202739-37-5)
- 1-(5-(2-Hydroxy-5-methoxy-3-nitrophenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)ethan-1-one (CAS 876941-46-7)
- N-(4-Bromobenzyl)-1-(2-fluorophenyl)methanamine (CAS 1019557-51-7)
- 2-((2-(Furan-2-yl)-2-oxoethyl)thio)pyrimidin-4(3H)-one (CAS 729570-18-7)
- 4-Methoxy-3-Butylphthalide (CAS 74459-22-6)
- tert-butyl 3-(difluoromethylidene)azetidine-1-carboxylate (CAS 1824293-92-6)
- 4-Amino-2-methyltetrahydro-2H-thiopyran 1,1-dioxide hydrochloride (CAS 2137613-27-3)
- 2-{[2-(2,2-Diphenylacetyl)hydrazino]carbonyl}cyclohexanecarboxylic acid (CAS 900592-36-1)
- Semaglutide impurity 23 (CAS CATO-C4X-222623)
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