[3-(difluoromethyl)-5h,6h,7h,8h-[1,2,4]triazolo[4,3-a]pyridin-6-yl]methanol CAS 1394724-38-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1394724-38-9
Molecular FormulaC8H11F2N3O
Molecular Weight203.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

[3-(difluoromethyl)-5h,6h,7h,8h-[1,2,4]triazolo[4,3-a]pyridin-6-yl]methanol CAS 1394724-38-9 chemical structure

Description

CATO manufactures [3-(difluoromethyl)-5h,6h,7h,8h-[1,2,4]triazolo[4,3-a]pyridin-6-yl]methanol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

CATO supplies [3-(difluoromethyl)-5h,6h,7h,8h-[1,2,4]triazolo[4,3-a]pyridin-6-yl]methanol (CAS 1394724-38-9), a certified reference material (molecular formula C8H11F2N3O, MW 203.19 g/mol) for analytical method development and quality control.

The molecular framework of [3-(difluoromethyl)-5h,6h,7h,8h-[1,2,4]triazolo[4,3-a]pyridin-6-yl]methanol (C8H11F2N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC8H11F2N3O
Molecular Weight203.19 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF-containing
Nitrogen Atoms3

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