Azilsartan Impurity 27 CAS 139481-44-0
| CAS No. | 139481-44-0 |
| Molecular Formula | C25H21N3O3 |
| Molecular Weight | 411.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Azilsartan Impurity 27 (C25H21N3O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Azilsartan Impurity 27 (CAS 139481-44-0) is a certified pharmaceutical impurity reference standard with the molecular formula C25H21N3O3 and a molecular weight of 411.45 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Azilsartan Impurity 27 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H21N3O3 |
| Molecular Weight | 411.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 3 |
Related Azilsartan Standards
- Azilsartan Impurity 101 (CAS 1857365-17-3)
- Azilsartan Impurity 181 (CAS CATO-C4X-1096181)
- Azilsartan Impurity 38 (CAS 1225044-11-0)
- Azilsartan Impurity 167 (CAS CATO-C4X-1096167)
- Azilsartan Impurity 15 (CAS 1442400-65-8)
- Azilsartan Impurity 22 (CAS CATO-C4X-109622)
- Azilsartan Impurity 6 (CAS 1696392-11-6)
- Azilsartan Impurity 12 (CAS 1499167-72-4)
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- 4-Amino-2,6-difluorobenzonitrile (CAS 207297-92-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com