Azilsartan Impurity 12 CAS 1499167-72-4
| CAS No. | 1499167-72-4 |
| Molecular Formula | C23H20N4O4 |
| Molecular Weight | 416.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Azilsartan Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Azilsartan Impurity 12 (CAS 1499167-72-4, C23H20N4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Azilsartan Impurity 12 (C23H20N4O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C23H20N4O4 |
| Molecular Weight | 416.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 4 |
Related Azilsartan Standards
- Azilsartan Impurity 22 (CAS CATO-C4X-109622)
- Azilsartan Impurity 6 (CAS 1696392-11-6)
- Azilsartan Impurity 15 (CAS 1442400-65-8)
- Azilsartan Impurity 101 (CAS 1857365-17-3)
- Azilsartan Impurity 124 (CAS CATO-C4X-1096124)
- Azilsartan Impurity 133 (CAS CATO-C4X-1096133)
- Azilsartan Impurity 181 (CAS CATO-C4X-1096181)
- Azilsartan Impurity 38 (CAS 1225044-11-0)
Recommended Standards
- N-[2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindolin-4-yl]-7-(hydroxyamino)-7-oxo-heptanamide (CAS 2758388-35-9)
- Omeprazole Impurity 8 (CAS 139482-04-5)
- N-(4-methoxybenzyl)-2-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-carbonyl)benzamide (CAS 861209-41-8)
- Proxyphylline Impurity 3 (CAS CATO-C4X-24403)
- Progesterone Impurity 48 (CAS 115387-31-0)
- Perospirone Impurity 33 (CAS CATO-C4X-245833)
- Selexipag Impurity 50 (CAS CATO-C4X-196150)
- 4-Chlorobenzyl Alcohol (CAS 873-76-7)
- 5-(4-Bromophenyl)-5-oxopentanoic acid (CAS 35333-26-7)
- Acid Green 25 (CAS 4403-90-1)
- 1-Methyltetrazole-5-methanamine Dihydrochloride (CAS 1803596-39-5)
- 3-Benzyloxy-2-chloro-6-fluorophenylboronic acid (CAS 957062-67-8)
- 5-Hydroxyisoquinoline-1-carbonitrile (CAS 90947-06-1)
- Tau Peptide (304-318) trifluoroacetate salt (CAS 330456-49-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com