Candesartan Cilexetil Impurity 9 CAS 139481-72-4
| CAS No. | 139481-72-4 |
| Molecular Formula | C43H34N6O3 |
| Molecular Weight | 682.77 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Candesartan Cilexetil Impurity 9 (CAS 139481-72-4, C43H34N6O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Candesartan Cilexetil Impurity 9 (C43H34N6O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Candesartan Cilexetil Impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C43H34N6O3 |
| Molecular Weight | 682.77 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 30.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 6 |
Related Candesartan Standards
- Candesartan Methyl Ester N1-Trityl Methoxy Analog (CAS 1246815-58-6)
- Candesartan Cilexetil Impurity 42 (CAS CATO-C4X-123442)
- Candesartan N2-Trityl Methoxy Analog (CAS 1797918-38-7)
- Candesartan Cilexetil Impurity 35 (CAS 1867269-67-7)
- Candesartan Cilexetil Impurity 15 (CAS 1797985-81-9)
- Candesartan Cilexetil Impurity 17 (CAS 856414-35-2)
- Candesartan Impurity 7 (CAS CATO-C4X-15727)
- Candesartan Cilexetil Impurity 44 (CAS CATO-C4X-123444)
Recommended Standards
- Posaconazole Impurity 172 (CAS CATO-C4X-1208172)
- Dabigatran Impurity 99 (CAS CATO-C4X-108999)
- Posaconazole Impurity 60 (CAS CATO-C4X-120860)
- N-Trityl Candesartan Methyl Ester Methoxy Analogue (CAS 1797136-91-4)
- Deoxycholic acid Impurity 16 (CAS CATO-C4X-335916)
- Esmolol Impurity 76 (CAS CATO-C4X-189176)
- Ibuprofen impurity 01 (CAS 95093-58-6)
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- 3-Chloro-n-methylbenzene-1-sulfonamide (CAS 16937-19-2)
- Des-[Oct-γ-Glu-AEEA-AEEA]-Semaglutide (CAS CATO-C4X-2226112)
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