5-chloro-3-nitro-2-(propan-2-yloxy)pyridine CAS 1395035-46-7
| CAS No. | 1395035-46-7 |
| Molecular Formula | C8H9ClN2O3 |
| Molecular Weight | 216.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-chloro-3-nitro-2-(propan-2-yloxy)pyridine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-chloro-3-nitro-2-(propan-2-yloxy)pyridine (CAS 1395035-46-7), molecular formula C8H9ClN2O3 and molecular weight 216.62 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 5-chloro-3-nitro-2-(propan-2-yloxy)pyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 216.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-chloro-3-nitro-2-(propan-2-yloxy)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9ClN2O3 |
| Molecular Weight | 216.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related chloro Standards
- Ethyl 6-chloro-3-hydrazinylpyridazine-4-carboxylate (CAS 1073488-86-4)
- 2-(4-Chloro-2-nitrophenoxy)ethan-1-amine (CAS 1183594-44-6)
- Ethyl 3-chloro-2-oxopyrazine-1(2H)-carboxylate (CAS 1194374-11-2)
- Ethyl 2-(5-chloro-1-methyl-1h-imidazol-2-yl)-2-oxoacetate (CAS 1210133-00-8)
- 3-(3-Chloro-4-hydroxyphenyl)-3-hydroxypropanoic acid (CAS 1248246-33-4)
- 2-(5-Chloro-2-nitrophenoxy)ethan-1-amine (CAS 1248814-38-1)
- 2-(3-Chloro-4-nitrophenoxy)ethan-1-amine (CAS 1249187-43-6)
- 2-Chloro-6-(methoxymethoxy)benzoic acid (CAS 1253188-17-8)
Recommended Standards
- Methyl 4-chloro-5-hydroxy-2-methoxybenzoate (CAS 1394952-48-7)
- 2-Chloro-4-isopropoxy-5-nitropyridine (CAS 1462950-90-8)
- Ethyl 6-chloro-3-methoxypyrazine-2-carboxylate (CAS 1393547-14-2)
- Ethyl 2-(chloromethyl)-6-oxo-1,6-dihydropyrimidine-5-carboxylate (CAS 150065-26-2)
- 2-Methanesulfonylpyrimidin-5-amine (CAS 56621-92-2)
- 6-Bromo-3-nitroquinolin-4(1H)-one (CAS 1429502-75-9)
- 3,5-Dibromo-2-(trifluoromethoxy)aniline (CAS 1803817-52-8)
- (S)-2-Amino-2-(pyridin-3-yl)acetic acid (CAS 1240587-42-1)
- 3-Chloro-4-fluoro-3-(4-fluorophenyl)-propiophenone (CAS 898768-49-5)
- N-(tert-Butyl)-3-methylpyridin-2-amine (CAS 1235305-63-1)
- Emtricitabine impurity 54 (CAS 145397-26-8)
- 3-(Cyanomethylene)cyclobutane-1-carbonitrile (CAS 1153949-98-4)
- 2-(3-ethynylcyclobutyl)propan-2-ol (CAS 1942858-71-0)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
Why CATO?
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