Methyl 4-chloro-5-hydroxy-2-methoxybenzoate CAS 1394952-48-7
| CAS No. | 1394952-48-7 |
| Molecular Formula | C9H9ClO4 |
| Molecular Weight | 216.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 4-chloro-5-hydroxy-2-methoxybenzoate.
Methyl 4-chloro-5-hydroxy-2-methoxybenzoate (CAS 1394952-48-7), molecular formula C9H9ClO4 and molecular weight 216.62 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Methyl 4-chloro-5-hydroxy-2-methoxybenzoate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 216.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 4-chloro-5-hydroxy-2-methoxybenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9ClO4 |
| Molecular Weight | 216.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
Related Methyl Standards
- Ethyl 6-chloro-3-hydrazinylpyridazine-4-carboxylate (CAS 1073488-86-4)
- 2-(4-Chloro-2-nitrophenoxy)ethan-1-amine (CAS 1183594-44-6)
- Ethyl 3-chloro-2-oxopyrazine-1(2H)-carboxylate (CAS 1194374-11-2)
- Ethyl 2-(5-chloro-1-methyl-1h-imidazol-2-yl)-2-oxoacetate (CAS 1210133-00-8)
- 3-(3-Chloro-4-hydroxyphenyl)-3-hydroxypropanoic acid (CAS 1248246-33-4)
- 2-(5-Chloro-2-nitrophenoxy)ethan-1-amine (CAS 1248814-38-1)
- 2-(3-Chloro-4-nitrophenoxy)ethan-1-amine (CAS 1249187-43-6)
- 2-Chloro-6-(methoxymethoxy)benzoic acid (CAS 1253188-17-8)
Recommended Standards
- Ethyl 6-chloro-3-methoxypyrazine-2-carboxylate (CAS 1393547-14-2)
- 5-chloro-3-nitro-2-(propan-2-yloxy)pyridine (CAS 1395035-46-7)
- Ethyl 2-(6-chloro-4-oxo-1,4-dihydropyrimidin-2-yl)acetate (CAS 1384070-82-9)
- 2-Chloro-4-isopropoxy-5-nitropyridine (CAS 1462950-90-8)
- 2-((2R,3R)-4-(Anthracen-9-yl)-3-(tert-butyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine (CAS 1542796-14-4)
- Piperazine DL-Malate (CAS 14852-14-3)
- 1-(4-Methoxyphenoxy)-3-(4-methylpiperazin-1-yl)propan-2-ol dihydrochloride (CAS 470474-70-5)
- 6-Iodo-1,2,3,4-tetrahydroisoquinoline (CAS 72299-61-7)
- 2-methyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)propan-2-ol (CAS 1415793-95-1)
- Calcium Carbide (CAS 75-20-7)
- 3-Bromo-1H-indazol-4-amine (CAS 885521-25-5)
- 5-Amino-1-(2-chlorobenzyl)-N-(2,3-dimethylphenyl)-1H-1,2,3-triazole-4-carboxamide (CAS 899981-50-1)
- Cefuroxime Sodium EP Impurity H(Cefuroxime Axetil EP Impurity E) (CAS 947723-87-7)
- Peptide 441 (CAS CATO-CPTD788441)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com