(E)-N-(2,4-dimethoxyphenyl)-3-(4-(trifluoromethoxy)phenyl)acrylamide CAS 882082-42-0
| CAS No. | 882082-42-0 |
| Molecular Formula | C18H16F3NO4 |
| Molecular Weight | 367.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (E)-N-(2,4-dimethoxyphenyl)-3-(4-(trifluoromethoxy)phenyl)acrylamide (C18H16F3NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
(E)-N-(2,4-dimethoxyphenyl)-3-(4-(trifluoromethoxy)phenyl)acrylamide (CAS 882082-42-0), molecular formula C18H16F3NO4 and molecular weight 367.32 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (E)-N-(2,4-dimethoxyphenyl)-3-(4-(trifluoromethoxy)phenyl)acrylamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H16F3NO4 |
| Molecular Weight | 367.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- alpha-(Trifluoromethyl)-DL-phenylalanine, N-CBZ protected (CAS 139520-45-9)
- (S)-2-(((benzyloxy)carbonyl)amino)-3-(4-(trifluoromethyl)phenyl)propanoic acid (CAS 921623-47-4)
- (S)-2-(((Benzyloxy)carbonyl)amino)-3-(3-(trifluoromethyl)phenyl)propanoic acid (CAS 1270285-74-9)
- 2-(2-Ethoxy-4-formylphenoxy)-N-[3-(trifluoromethyl)phenyl]acetamide (CAS 486995-03-3)
- 1'-Benzyl-5-chlorospiro[indoline-3,4'-piperidin]-2-one (CAS 161919-79-5)
- 5-Methyl-4-nitroimidazole (CAS 14003-66-8)
- Ethyl 4-((4-oxo-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)butanoate (CAS 433328-42-8)
- (3S,4S)-4-Aminopiperidin-3-ol (CAS 1206906-33-3)
- (S)-2-amino-4-methyl-N-(4-phenoxyphenyl)pentanamide (CAS 1217713-86-4)
- 2-Amino-N-(4-fluorophenyl)acetamide (CAS 347910-19-4)
- (4R,5R)-N-[[(4R,5R)-4,5-Dihydro-5-methyl-4-phenyl-2-oxazolyl]methyl]-4,5-dihydro-5-methyl-4-phenyl-2-oxazolemethanamine (CAS 474364-65-3)
- Nitrosamines Impurity 32 (CAS 101-25-7)
- (1R,3S,5S)-6-Methyl-7-oxo-6-azabicyclo[3.2.0]heptan-3-yl acetate (CAS 524018-45-9)
- Palmitoyl Tripeptide-8 TFA salt (CAS 936544-53-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com