2-(3,4-Dichlorophenyl)-5-oxotetrahydrofuran-3-carboxylic acid CAS 1399658-66-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1399658-66-2
Molecular FormulaC11H8Cl2O4
Molecular Weight275.08 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(3,4-Dichlorophenyl)-5-oxotetrahydrofuran-3-carboxylic acid CAS 1399658-66-2 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

2-(3,4-Dichlorophenyl)-5-oxotetrahydrofuran-3-carboxylic acid (CAS 1399658-66-2), molecular formula C11H8Cl2O4 and molecular weight 275.08 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(3,4-Dichlorophenyl)-5-oxotetrahydrofuran-3-carboxylic acid (C11H8Cl2O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC11H8Cl2O4
Molecular Weight275.08 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentCl-containing

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