Cyclophosphamide impurity 40 CAS CATO-C4X-230640
| CAS No. | CATO-C4X-230640 |
| Molecular Formula | C7H13Cl2N2O3P |
| Molecular Weight | 275.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Cyclophosphamide impurity 40 (CAS CATO-C4X-230640), a pharmacopoeial impurity reference standard (molecular formula C7H13Cl2N2O3P, MW 275.07 g/mol) used for the identification and quantification of trace impurities in APIs.
Cyclophosphamide impurity 40 (C7H13Cl2N2O3P) contains an amide group, a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Cyclophosphamide impurity 40 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H13Cl2N2O3P |
| Molecular Weight | 275.07 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.5 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Cyclophosphamide Standards
- 4-Oxo Cyclophosphamide (CAS 27046-19-1)
- Cyclophosphamide Impurity 12 (CAS 78149-83-4)
- Cyclophosphamide Impurity 19 (CAS 22089-17-4)
- Cyclophosphamide Impurity 12 (CAS CATO-C4X-230612)
- Cyclophosphamide Impurity 47 (CAS CATO-C4X-230647)
- Cyclophosphamide impurity 01 (CAS 35144-64-0)
- Cyclophosphamide Impurity 9 (CAS 40277-05-2)
- Cyclophosphamide Impurity 22 (CAS 3308-51-8)
Recommended Standards
- 3-Hydroxy Anagrelide-13C3 (CAS 1219393-12-0)
- 5-(3-Bromothiophen-2-yl)-1,2,4-oxadiazole-3-carboxylic acid (CAS 1340387-15-6)
- Ifosfamide Impurity 1 (CAS 72578-71-3)
- 2-(3,4-Dichlorophenyl)-5-oxotetrahydrofuran-3-carboxylic acid (CAS 1399658-66-2)
- Avibactam Impurity 29 (CAS CATO-C4X-134829)
- Avatrombopag impurity 135 (CAS CATO-C4X-2234135)
- Prucalopride Impurity 52 (CAS CATO-C4X-103852)
- 1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-chloro-ethanone-d6 (CAS 1329838-71-2)
- 4-Amino-6-bromoisochromane Hydrochloride (CAS 676134-73-9)
- Argatroban Impurity 22 (CAS CATO-C4X-100722)
- tert-Butyl 2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate (CAS 205383-87-5)
- (Z)-3-phenyl-2-(propylimino)thiazolidin-4-one (CAS 854107-48-5)
- 6-Chloro-3-(4-chlorophenyl)pyridazine-4-carboxylic acid (CAS 1437433-87-8)
- Acetyl tetrapeptide-3 (CAS 827306-88-7)
Why CATO?
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