5'-amino-1',2'-dihydrospiro[cyclopropane-1,3'-indole]-2'-one CAS 1399663-06-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5'-amino-1',2'-dihydrospiro[cyclopropane-1,3'-indole]-2'-one.

5'-amino-1',2'-dihydrospiro[cyclopropane-1,3'-indole]-2'-one (CAS 1399663-06-9), molecular formula C10H16N2O and molecular weight 180.25 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5'-amino-1',2'-dihydrospiro[cyclopropane-1,3'-indole]-2'-one (C10H16N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5'-amino-1',2'-dihydrospiro[cyclopropane-1,3'-indole]-2'-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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