4-ethynyl-1-(2,2,2-trifluoroethyl)pyrazole CAS 1400287-67-3
| CAS No. | 1400287-67-3 |
| Molecular Formula | C7H9F3N2 |
| Molecular Weight | 178.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-ethynyl-1-(2,2,2-trifluoroethyl)pyrazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 4-ethynyl-1-(2,2,2-trifluoroethyl)pyrazole (CAS 1400287-67-3), a certified reference material (molecular formula C7H9F3N2, MW 178.15 g/mol) for analytical method development and quality control.
The molecular framework of 4-ethynyl-1-(2,2,2-trifluoroethyl)pyrazole (C7H9F3N2) is characterized by a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H9F3N2 |
| Molecular Weight | 178.15 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related ethynyl Standards
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- Methyl 3-ethynyl-4-fluorobenzoate (CAS 1263286-05-0)
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- Methyl 2-ethynyl-6-fluorobenzoate (CAS 2551119-21-0)
- Methyl 3-ethynyl-5-fluorobenzoate (CAS 914944-24-4)
- Methyl 4-ethynyl-2-fluorobenzoate (CAS 692277-73-9)
- Ethyl 2-(4-ethynyl-1H-pyrazol-1-yl)acetate (CAS 2098072-46-7)
- Ethyl 4-ethynyl-1-methyl-1H-pyrazole-3-carboxylate (CAS 2228362-38-5)
Recommended Standards
- 2-Aminopyrazolo[1,5-a]pyrimidine-3-carboxylic Acid (CAS 1394003-86-1)
- 3,5-Dimethyl-1-(2,2,2-trifluoroethyl)-1H-pyrazole (CAS 141354-19-0)
- 2-Amino-[1,2,4]triazolo[1,5-a]pyridine-6-carboxylic acid (CAS 1369271-47-5)
- methyl 4-azidopyridine-2-carboxylate (CAS 1431470-10-8)
- 2,3,4,8,9-Pentachlorodibenzofuran mixed congeners (CAS 67517-48-0)
- 2-(5-Chloro-1-methyl-1H-indol-3-yl)ethanol (CAS 850406-55-2)
- Ethyl 2-(4-(2,5-dioxopiperazin-1-yl)phenyl)acetate (CAS 1956336-09-6)
- 4-Chloro-2-(methylthio)-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS 51660-15-2)
- 1-(Dimethylamino)-4-phenoxypent-1-en-3-one (CAS 338976-01-5)
- 9H-Naphth[3,2,1-kl]acridinium, 2,5-dimethyl-8-[(4-methylphenyl)amino]-9-oxo-, methyl sulfate (1:1) (CAS 72906-37-7)
- 2-[(E)-(3,5-Dibromo-2-hydroxyphenyl)methylidene]-N-methyl-1-hydrazinecarbothioamide (CAS 375793-82-1)
- 1-(2-(Benzyloxy)-6-hydroxyphenyl)ethan-1-one (CAS 4047-24-9)
- 3-(2,4-Difluorophenoxy)azetidine (CAS 954225-05-9)
- Eledoisin Related Peptide (CAS 2990-43-4)
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