Methyl 3-ethynyl-5-fluorobenzoate CAS 914944-24-4
| CAS No. | 914944-24-4 |
| Molecular Formula | C10H7FO2 |
| Molecular Weight | 178.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Methyl 3-ethynyl-5-fluorobenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Methyl 3-ethynyl-5-fluorobenzoate (CAS 914944-24-4), molecular formula C10H7FO2 and molecular weight 178.16 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 3-ethynyl-5-fluorobenzoate (C10H7FO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7FO2 |
| Molecular Weight | 178.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Methyl Standards
- Methyl 3-ethynyl-4-fluorobenzoate (CAS 1263286-05-0)
- Methyl 4-ethynyl-3-fluorobenzoate (CAS 1459216-15-9)
- Methyl 2-ethynyl-6-fluorobenzoate (CAS 2551119-21-0)
- Methyl 4-ethynyl-2-fluorobenzoate (CAS 692277-73-9)
- 4-ethynyl-1-(2,2,2-trifluoroethyl)pyrazole (CAS 1400287-67-3)
- 5-ethynyl-2-(trifluoromethyl)tetrahydropyran (CAS 2306265-32-5)
- Ethyl 2-(4-ethynyl-1H-pyrazol-1-yl)acetate (CAS 2098072-46-7)
- Ethyl 4-ethynyl-1-methyl-1H-pyrazole-3-carboxylate (CAS 2228362-38-5)
Recommended Standards
- Methyl 3-(4-fluorophenyl)propiolate (CAS 42122-44-1)
- Methyl 3-(3-fluorophenyl)propiolate (CAS 221148-38-5)
- N-Acetyl-DL-aspartic-2,3,3-d3 Acid (CAS 89829-69-6)
- Methyl 3-(2-fluorophenyl)propiolate (CAS 340772-55-6)
- 2-(4-Chlorophenyl)-6-methylimidazo[1,2-a]pyridine (CAS 103844-28-6)
- N-(3-Chlorophenyl)-3,5-difluorobenzenesulfonamide (CAS 1089622-73-0)
- 2-[4-(hydroxymethyl)phenoxy]acetonitrile (CAS 123226-38-0)
- 2-Amino-N-(naphthalen-2-yl)propanamide (CAS 20723-89-1)
- 1-Bromo-2-[chloro(difluoro)-methoxy]-3-nitro-benzene (CAS 1417566-51-8)
- 1-(5-(Trifluoromethyl)pyridin-2-yl)piperazine (CAS 132834-58-3)
- 3,4-Dimethoxycinnamic Acid (CAS 2316-26-9)
- N-(6-Fluoropyridin-2-yl)acetamide (CAS 258343-71-4)
- Cefuroxime Impurity 21 (CAS CATO-C4X-124521)
- Insulin Degludec Impurity 11 (CAS CATO-C4X-215711)
Why CATO?
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