Cinacalcet Impurity 56 CAS 1400812-64-7
| CAS No. | 1400812-64-7 |
| Molecular Formula | C22H18F3NO2 |
| Molecular Weight | 385.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cinacalcet Impurity 56.
CATO supplies Cinacalcet Impurity 56 (CAS 1400812-64-7), a pharmacopoeial impurity reference standard (molecular formula C22H18F3NO2, MW 385.38 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Cinacalcet Impurity 56 (C22H18F3NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Cinacalcet Impurity 56 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H18F3NO2 |
| Molecular Weight | 385.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Cinacalcet Standards
- Cinacalcet Impurity 70 (CAS CATO-C4X-105970)
- Cinacalcet Impurity 64 (CAS CATO-C4X-105964)
- Cinacalcet Impurity 100 (CAS CATO-C4X-1059100)
- Cinacalcet Impurity 101 (CAS CATO-C4X-1059101)
- Cinacalcet Impurity 99 (CAS CATO-C4X-105999)
- Cinacalcet Impurity 32 (CAS CATO-C4X-105932)
- Cinacalcet N-Oxide (CAS 1229224-94-5)
- Cinacalcet Impurity 81 (CAS CATO-C4X-105981)
Recommended Standards
- PD1-PDL1-IN 1 (CAS 2005454-12-4)
- 1-[4-(morpholine-4-sulfonyl)-2-nitrophenyl]pyrrolidine-2-carboxylic acid (CAS 1008006-09-4)
- N-Benzyl-N-(4-methoxyphenyl)-3-(trifluoromethyl)benzamide (CAS 338400-64-9)
- N4-(3-Aminophenyl)-5-fluoro-N2-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine (CAS 1166389-11-2)
- Cinacalcet Impurity 104 (CAS CATO-C4X-1059104)
- Nimodipine Impurity N15 (CAS 101072-61-1)
- Ponatinib Impurity 39 (CAS 2702457-83-6)
- 6-Chloro-1H-benzo[d]imidazol-1-amine (CAS 63282-63-3)
- 5-Ethyl-4-fluoro-1H-pyrazole-3-carboxamide (CAS 957129-52-1)
- (2S,3S)-2-Amino-3,4-dimethylpentanoic acid (CAS 23262-01-3)
- ((2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-methoxytetrahydro-2H-pyran-2-yl)methyl benzoate (CAS 21056-50-8)
- 3-Chloro-N-(3-hydroxyphenyl)-2,2-dimethylpropanamide (CAS 303986-05-2)
- 2,2,2-Trifluoro-1-(4-isopropylcyclohexyl)ethan-1-ol (CAS 1874551-09-3)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com