Cinacalcet Impurity 81 CAS CATO-C4X-105981
| CAS No. | CATO-C4X-105981 |
| Molecular Formula | C22H22F3NO |
| Molecular Weight | 373.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 373.41 g/mol gives Cinacalcet Impurity 81 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Cinacalcet Impurity 81 (CAS CATO-C4X-105981), a pharmacopoeial impurity reference standard (molecular formula C22H22F3NO, MW 373.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Cinacalcet Impurity 81 (C22H22F3NO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 373.41 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Cinacalcet Impurity 81 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H22F3NO |
| Molecular Weight | 373.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Cinacalcet Standards
- Cinacalcet N-Oxide (CAS 1229224-94-5)
- Cinacalcet Impurity 66 (CAS CATO-C4X-105966)
- Cinacalcet impurity 88 (CAS CATO-C4X-105988)
- Cinacalcet Impurity N52 (CAS 1005450-55-4)
- Cinacalcet Impurity 41 (CAS CATO-C4X-105941)
- Cinacalcet Impurity 42 (CAS CATO-C4X-105942)
- Cinacalcet Impurity 43 (CAS CATO-C4X-105943)
- Cinacalcet Impurity 44 (CAS CATO-C4X-105944)
Recommended Standards
- Terazosin EP Impurity G (CAS 105356-89-6)
- tert-Butyl 4-(2-amino-1-(4-(trifluoromethyl)phenyl)ethyl)piperazine-1-carboxylate (CAS 444892-59-5)
- Terazosin EP Impurity H (CAS 105356-90-9)
- tert-Butyl (1-(2-amino-1-(4-(trifluoromethyl)phenyl)ethyl)pyrrolidin-3-yl)carbamate (CAS 886365-38-4)
- Elagolix Impurity 13 (CAS CATO-C4X-206813)
- Phenylephrine Impurity 52 (CAS 1785420-81-6)
- Sitagliptin Impurity 106 (CAS CATO-C4X-1144106)
- 4-(tert-Pentyl)phenyl 3-pyrrolidinyl etherhydrochloride (CAS 1219982-42-9)
- Ethyl 2-(((1r,4r)-4-((tert-butoxycarbonyl)amino)cyclohexyl)oxy)acetate (CAS 1315498-59-9)
- 7-Azabicyclo[2.2.1]heptane-1,4-dicarboxylic acid hydrochloride (CAS 943620-88-0)
- N-(3-(6-(4-Cyclopropylpiperazin-1-yl)pyridazin-3-yl)phenyl)acetamide (CAS 919495-44-6)
- 2-Methoxy-N-(3-(prop-2-yn-1-yl)benzo[d]thiazol-2(3H)-ylidene)benzamide (CAS 865181-10-8)
- 2-Phenylpent-2-enal (CAS 3491-63-2)
- Liraglutide Impurity 18 TFA Salt (CAS CATO-C4X-199218)
Why CATO?
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