(2R)-4,4-Difluoropyrrolidine-2-carboxylic acid CAS 1401332-74-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1401332-74-8
Molecular FormulaC5H7F2NO2
Molecular Weight151.11 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2R)-4,4-Difluoropyrrolidine-2-carboxylic acid CAS 1401332-74-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 151.11 g/mol gives (2R)-4,4-Difluoropyrrolidine-2-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(2R)-4,4-Difluoropyrrolidine-2-carboxylic acid (CAS 1401332-74-8) is a high-purity analytical reference standard with the molecular formula C5H7F2NO2 and a molecular weight of 151.11 g/mol.

Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, (2R)-4,4-Difluoropyrrolidine-2-carboxylic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 151.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (2R)-4,4-Difluoropyrrolidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC5H7F2NO2
Molecular Weight151.11 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityLight-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1991
Halogen ContentF-containing
Nitrogen Atoms1

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