4,4-Difluoropyrrolidine-3-carboxylic acid CAS 1538809-33-4
| CAS No. | 1538809-33-4 |
| Molecular Formula | C5H7F2NO2 |
| Molecular Weight | 151.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C5H7F2NO2, 4,4-Difluoropyrrolidine-3-carboxylic acid contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 151.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4,4-Difluoropyrrolidine-3-carboxylic acid (CAS 1538809-33-4), molecular formula C5H7F2NO2 and molecular weight 151.11 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4,4-Difluoropyrrolidine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H7F2NO2 |
| Molecular Weight | 151.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoropyrrolidine Standards
- 4,4-difluoropyrrolidine-2-carboxylic acid (CAS 1073555-68-6)
- (2R)-4,4-Difluoropyrrolidine-2-carboxylic acid (CAS 1401332-74-8)
- (S)-3,3-difluoropyrrolidine-2-carboxylic acid (CAS 1821782-74-4)
- (2S)-4,4-difluoropyrrolidine-2-carboxylic acid (CAS 52683-81-5)
- (R)-4,4-difluoropyrrolidine-2-carboxamide (CAS 1315304-75-6)
- 4,4-Difluoropyrrolidine-2-carboxamide (CAS 1461666-26-1)
- (2S)-4,4-Difluoropyrrolidine-2-carboxamide (CAS 719267-96-6)
- Methyl 4,4-difluoropyrrolidine-2-carboxylate (CAS 1416499-38-1)
Recommended Standards
- (R)-3,3-Difluoro-5-(hydroxymethyl)pyrrolidin-2-one (CAS 1544279-19-7)
- 3,3-Difluoro-5-hydroxypiperidin-2-one (CAS 1256080-98-4)
- 3,4-difluoro-1h-pyrrole-2-carboxylic acid (CAS 160561-81-9)
- 1-amino-3,3-difluoro-cyclobutanecarboxylic acid (CAS 1225532-86-4)
- N-(benzo[d][1,3]dioxol-5-yl)-1-(2-chlorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 400077-83-0)
- 1-(4-Chlorophenyl)-2-cyclopropylquinazolin-4(1H)-one (CAS 95216-40-3)
- 1-(Bis(4-chlorophenyl)methyl)piperazine (CAS 27469-61-0)
- benzyl 3-hydroxy-3-methylpyrrolidine-1-carboxylate (CAS 1262409-80-2)
- 4-(2-Oxopyrrolidin-1-yl)benzene-1-sulfonamide (CAS 36090-27-4)
- 1-Methanesulfonyl-4-[4-(trifluoromethoxy)phenoxy]benzene (CAS 286844-91-5)
- 1,3,6,8-Tetrabromopyrene (CAS 128-63-2)
- 3-(Cyclopentyloxy)-2-fluoro-4-methoxyphenylboronic acid (CAS 1793003-66-3)
- 2-((2-Oxo-2-phenylethyl)thio)nicotinaldehyde (CAS 887577-13-1)
- Neuropeptide K, porcine (CAS 106441-70-7)
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