2-(Difluoromethyl)naphthalene CAS 140135-76-8
| CAS No. | 140135-76-8 |
| Molecular Formula | C11H8F2 |
| Molecular Weight | 178.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-(Difluoromethyl)naphthalene (C11H8F2) contains fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 178.18 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2-(Difluoromethyl)naphthalene (CAS 140135-76-8), a certified reference material (molecular formula C11H8F2, MW 178.18 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(Difluoromethyl)naphthalene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8F2 |
| Molecular Weight | 178.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
Related Difluoromethyl Standards
- trans-4-(difluoromethyl)cyclohexane-1-carboxylic acid (CAS 1115331-05-9)
- 4-(Difluoromethyl)cyclohexanecarboxylic Acid (CAS 1378852-94-8)
- 1-(Difluoromethyl)cyclohexane-1-carboxylic acid (CAS 1781320-56-6)
- 1-(Difluoromethyl)naphthalene (CAS 53731-26-3)
- Ethyl 3-(difluoromethyl)cyclobutane-1-carboxylate (CAS 2120250-04-4)
- Difluoromethyl 2-fluorophenyl sulphide (CAS 1228781-83-6)
- 6-(Difluoromethyl)-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one (CAS 1204298-76-9)
- 4-(Difluoromethyl)thiophene-3-carboxylic acid (CAS 1783508-32-6)
Recommended Standards
- 4,4-Difluoro-1-methylcyclohexane-1-carboxylic acid (CAS 1389313-41-0)
- 2-Hydroxy-4-methoxy-6-vinylbenzaldehyde (CAS 1403608-13-8)
- 5-Formyl-2,4-dimethylbenzoic acid (CAS 1379174-31-8)
- (E)-3-(2-hydroxy-4-methylphenyl)acrylic acid (CAS 1414838-29-1)
- 2-(Difluoromethyl)-3-iodo-5-methylpyridine-6-acetonitrile (CAS 1807137-47-8)
- (S)-3-amino-2-(3-(methylthio)benzyl)propanoic acid (CAS 914644-83-0)
- 4-[(carboxymethyl)sulfamoyl]-1-methyl-1h-pyrrole-2-carboxylic acid (CAS 1000933-49-2)
- 4-Hydroxy-6-methoxypyrimidine-2-carboxylic acid (CAS 1785505-43-2)
- Methyl (2S,4S)-4-[(2,2,2-trichloroacetyl)oxy]-2-pyrrolidinecarboxylate hydrochloride (CAS 1354485-00-9)
- 2-Amino-5-(3,5-dichlorophenyl)isonicotinic acid (CAS 1261987-76-1)
- Topiroxostat Impurity 4 (CAS 2459-09-8)
- 7-aminonorbornane-2,7-dicarboxylic acid (CAS 1432677-90-1)
- 2-(3-(Phenoxymethyl)phenyl)benzo[d]thiazole (CAS 400087-91-4)
- endo-Arg30-Semaglutide (CAS CATO-C4X-2226281)
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