4,4-Difluoro-1-methylcyclohexane-1-carboxylic acid CAS 1389313-41-0
| CAS No. | 1389313-41-0 |
| Molecular Formula | C8H12F2O2 |
| Molecular Weight | 178.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4,4-Difluoro-1-methylcyclohexane-1-carboxylic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4,4-Difluoro-1-methylcyclohexane-1-carboxylic acid (CAS 1389313-41-0), molecular formula C8H12F2O2 and molecular weight 178.18 g/mol, is a CATO reference standard with documented purity and traceability.
4,4-Difluoro-1-methylcyclohexane-1-carboxylic acid (C8H12F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4,4-Difluoro-1-methylcyclohexane-1-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H12F2O2 |
| Molecular Weight | 178.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 2,2-Difluoro-1-(4-methylpiperazin-1-yl)ethanone (CAS 121412-30-4)
- 6,8-difluoro-[1,2,4]triazolo[1,5-a]pyridin-2-amine (CAS 1643856-61-4)
- 8,8-Difluoro-1,4-dioxaspiro[4.5]decane (CAS 176251-49-3)
- 2-Ethyl-4,4-difluoro-2-hydroxycyclohexan-1-one (CAS 2839564-79-1)
- 4,4-Difluoro-2-methoxy-2-methylcyclohexan-1-one (CAS 2839564-85-9)
- 4,4-Difluoro-6,6-dimethyltetrahydro-2H-pyran-2-carbaldehyde (CAS 2791313-73-8)
- Ethyl 3,3-Difluoro-1-methylcyclobutanecarboxylate (CAS 227607-45-6)
- 2,2-Difluoro-2-(1,3-thiazol-2-yl)acetamide (CAS 1850835-10-7)
Recommended Standards
- 5-Formyl-2,4-dimethylbenzoic acid (CAS 1379174-31-8)
- 2-(Difluoromethyl)naphthalene (CAS 140135-76-8)
- 4-(Difluoromethyl)cyclohexanecarboxylic Acid (CAS 1378852-94-8)
- 2-Hydroxy-4-methoxy-6-vinylbenzaldehyde (CAS 1403608-13-8)
- 1-Bromo-4-(difluoromethyl)-2-fluoro-5-nitrobenzene (CAS 1807262-57-2)
- Histapyrrodine Hydrochloride (CAS 6113-17-3)
- Ethyl 3-(tetrahydrofuran-3-yl)propanoate (CAS 766539-77-9)
- 4,6-Dihydroxy-5-nitropyrimidine (CAS 2164-83-2)
- 6-(Benzyloxy)-3-(difluoromethyl)-1H-indole (CAS 2149598-55-8)
- 7-Ethoxybenzo[d]thiazole-2(3H)-thione (CAS 767583-07-3)
- 2-Chloro-N-(tetrahydro-1,1-dioxido-3-thienyl)acetamide (CAS 5612-41-9)
- N-(4-Hydroxy-3-(4-methylpiperazin-1-yl)phenyl)-2'-methyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)-[1,1'-biphenyl]-4-carboxamide (CAS 256227-77-7)
- Dexpanthenol Impurity 2 (CAS 18679-90-8)
- Semaglutide Sodium Salt (CAS CATO-C4X-222620)
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