5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(thiophen-3-yl)thiazole CAS 1402166-58-8
| CAS No. | 1402166-58-8 |
| Molecular Formula | C13H16BNO2S2 |
| Molecular Weight | 293.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(thiophen-3-yl)thiazole.
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(thiophen-3-yl)thiazole (CAS 1402166-58-8) is a high-purity analytical reference standard with the molecular formula C13H16BNO2S2 and a molecular weight of 293.21 g/mol.
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(thiophen-3-yl)thiazole (C13H16BNO2S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(thiophen-3-yl)thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H16BNO2S2 |
| Molecular Weight | 293.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Tetramethyl Standards
- 4-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)cyclohex-3-en-1-yl]morpholine (CAS 1046793-56-9)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(thiophen-2-yl)thiazole (CAS 1402166-57-7)
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(thiophen-2-yl)thiazole (CAS 1402166-59-9)
- 2-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-dihydroisoquinolin-1-one (CAS 1655495-97-8)
- 1-((5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)methyl)pyrrolidine (CAS 1218790-45-4)
- 1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-carbazole (CAS 1219637-88-3)
- 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-carbazole (CAS 1242412-60-7)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-carbazole (CAS 1255309-13-7)
Recommended Standards
- 1-[3,5-Bis(trifluoromethyl)phenyl]cyclobutanecarbonitrile (CAS 1260826-36-5)
- N,N-Diethyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanamine (CAS 1086111-20-7)
- Methyl 3-(2-fluorophenyl)-3-[(2,2,2-trifluoroacetyl)amino]propanoate (CAS 866050-44-4)
- N-cyclohexyl-3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propanamide (CAS 1980087-10-2)
- N-[4-(3-aminopropyl)phenyl]-N,N-dimethylamine (CAS 112103-97-6)
- 2-(Benzyloxy)-1,4-difluorobenzene (CAS 152434-79-2)
- (5-(2-Methoxyphenyl)pyridin-3-yl)boronic acid (CAS 1219737-10-6)
- N-cyclobutylazetidin-3-amine (CAS 1489480-50-3)
- 1-(4-Bromophenyl)-5-fluoro-1H-pyrazole (CAS 1784989-21-4)
- 6-(Naphthalen-2-ylsulfonyl)-5,6,7,8-tetrahydroquinazoline-2,4-diamine (CAS 60368-04-9)
- 5-Bromo-1-ethyl-1h-1,3-benzodiazol-2-amine (CAS 24786-56-9)
- 4-Bromo-1-((1r,4r)-4-((tert-butyldimethylsilyl)oxy)cyclohexyl)-1H-pyrazole (CAS 2306245-78-1)
- 2-[(Bis-trifluoromethyl-amino)-methyl]-pyrrolidine-1-carboxylic acid tert-butyl ester (CAS 1206524-01-7)
- Semaglutide Impurity 167 (CAS CATO-C4X-2226167)
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