Opicapone Impurity N3 CAS 1402714-41-3
| CAS No. | 1402714-41-3 |
| Molecular Formula | C16H12Cl2N4O6 |
| Molecular Weight | 427.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Opicapone Impurity N3.
Opicapone Impurity N3 (CAS 1402714-41-3) is a certified pharmaceutical impurity reference standard with the molecular formula C16H12Cl2N4O6 and a molecular weight of 427.20 g/mol.
Opicapone Impurity N3 (C16H12Cl2N4O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Opicapone Impurity N3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H12Cl2N4O6 |
| Molecular Weight | 427.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Opicapone Standards
- Opicapone Impurity 46 (CAS CATO-C4X-240446)
- Opicapone Impurity 52 (CAS CATO-C4X-240452)
- Opicapone Impurity 41 (CAS CATO-C4X-240441)
- Opicapone impurity 36 (CAS CATO-C4X-240436)
- Opicapone Impurity 5 (CAS CATO-C4X-24045)
- Opicapone Impurity 85 (CAS CATO-C4X-240485)
- Opicapone Impurity 88 (CAS CATO-C4X-240488)
- Opicapone Impurity 45 (CAS CATO-C4X-240445)
Recommended Standards
- Adenosine 5＇-diphosphate (CAS 58-64-0)
- (E)-3-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)vinyl)-N-(4-chlorophenyl)-1H-pyrazole-1-carboxamide (CAS 321534-56-9)
- Binimetinib Impurity 3 (CAS CATO-C4X-30503)
- 4-Bromo-1-methyl-2-phenyl-5-{[3-(trifluoromethyl)phenoxy]methyl}-2,3-dihydro-1H-pyrazol-3-one (CAS 937604-60-9)
- Relugolix Impurity 153 (CAS 3046102-25-1)
- Haloperidol EP Impurity F (CAS 1391052-67-7)
- Apixaban Impurity N3 (CAS 2413365-22-5)
- Isopentyl tetradecanoate (CAS 62488-24-8)
- 2-(4-Bromo-2,6-difluorophenyl)-1,3-dioxolane (CAS 773087-43-7)
- 3-Amino-4-[(2-methoxyethyl)amino]-n-methylbenzene-1-sulfonamide (CAS 1154276-26-2)
- 1-cyclobutyl-4-(piperidine-4-carbonyl)-1,4-diazepane (CAS 799557-73-6)
- 1-bromo-5-(ethanesulfonyl)pentane (CAS 1340221-41-1)
- 1,2,3,5-Tetrachloro-4,6-dinitrobenzene (CAS 28073-03-2)
- (Ser(PO?H?)3??·???)-Tau Peptide (379-408) trifluoroacetate salt (CAS 2022956-60-9)
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