3-((tert-Butyldimethylsilyl)oxy)-3-cyclohexyl-1-(2-iodophenyl)propan-1-one CAS 1402839-08-0
| CAS No. | 1402839-08-0 |
| Molecular Formula | C21H33IO2Si |
| Molecular Weight | 472.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-((tert-Butyldimethylsilyl)oxy)-3-cyclohexyl-1-(2-iodophenyl)propan-1-one (CAS 1402839-08-0), molecular formula C21H33IO2Si and molecular weight 472.48 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-((tert-Butyldimethylsilyl)oxy)-3-cyclohexyl-1-(2-iodophenyl)propan-1-one (C21H33IO2Si) is characterized by a steroid core, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-((tert-Butyldimethylsilyl)oxy)-3-cyclohexyl-1-(2-iodophenyl)propan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H33IO2Si |
| Molecular Weight | 472.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | I-containing |
Related tert Standards
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- 4-(3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-3-iodo-5-nitropyridine (CAS 1186310-82-6)
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- 5-(3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-2-chloro-3-iodopyridine (CAS 1203499-04-0)
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Recommended Standards
- Eugenol rutinoside (CAS 138772-01-7)
- 1-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-N-[(4-methylphenyl)methyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 321848-19-5)
- 2-(4-Bromo-3-chlorophenoxy)-6,7-dichloro-3-(trifluoromethyl)quinoxaline (CAS 478039-37-1)
- 2-((3-Cyano-6-phenyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinolin-2-yl)thio)-N-(4-methyloxazol-2-yl)acetamide (CAS 664999-17-1)
- Nifenazone (CAS 2139-47-1)
- 3-(benzyloxy)-6-methyl-4-oxo-4H-pyran-2-carboxylic acid (CAS 216581-47-4)
- 2-(Difluoromethyl)-5-ethynylpyridine (CAS 1211540-64-5)
- Tert-butyl 5-bromo-6-(trifluoromethoxy)indole-1-carboxylate (CAS 2227479-96-9)
- 5-(1,3-dioxan-2-yl)-1-methyl-1H-indazol-3-amine (CAS 1373350-39-0)
- 5-(Perfluoroethyl)thiazol-2-amine (CAS 1257329-76-2)
- Ethyl 2,6-dimethyl-4-(trifluoromethyl)nicotinate (CAS 200879-72-7)
- Atrasentan Impurity 146 (CAS 1058350-25-6)
- [4-[Bis(diethoxyphosphoryl)methyl]phenyl] carbamate (CAS 117758-87-9)
- Proinsulin C-Peptide (55-89) (human) (CAS 11097-48-6)
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