(3β)-3-[(tert-Butyldimethylsilyl)oxy]-chola-5,7-dien-24-ol CAS 146177-15-3
| CAS No. | 146177-15-3 |
| Molecular Formula | C30H52O2Si |
| Molecular Weight | 472.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (3β)-3-[(tert-Butyldimethylsilyl)oxy]-chola-5,7-dien-24-ol is closely related to a steroid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(3β)-3-[(tert-Butyldimethylsilyl)oxy]-chola-5,7-dien-24-ol (CAS 146177-15-3) is a high-purity analytical reference standard with the molecular formula C30H52O2Si and a molecular weight of 472.82 g/mol.
Based on its molecular formula C30H52O2Si, (3β)-3-[(tert-Butyldimethylsilyl)oxy]-chola-5,7-dien-24-ol contains a steroid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 472.82 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3β)-3-[(tert-Butyldimethylsilyl)oxy]-chola-5,7-dien-24-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C30H52O2Si |
| Molecular Weight | 472.82 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
Related tert Standards
- 3-((tert-Butyldimethylsilyl)oxy)-3-cyclohexyl-1-(2-iodophenyl)propan-1-one (CAS 1402839-08-0)
- 7-(3-((tert-Butyldimethylsilyl)oxy)propyl)-6-(1-ethoxyvinyl)-5-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS 821794-86-9)
- 4-(3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-3-iodo-5-nitropyridine (CAS 1186310-82-6)
- 5-((tert-Butyldimethylsilyl)oxy)-3-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole (CAS 1254473-78-3)
- 1-(5-((Tert-butyldimethylsilyl)oxy)-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-1-yl)-2,2-dimethylpropan-1-one (CAS 2390149-15-0)
- 5-(3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-2-chloro-3-iodopyridine (CAS 1203499-04-0)
- (3β)-3-[(tert-Butyldimethylsilyl)oxy]-chola-5,7-dien-24-oic Acid Methyl Ester (CAS 146177-13-1)
- (3β)-3-(tert-Butyldimethylsilyl)oxy-chol-5-en-24-oic Acid Methyl Ester (CAS 114011-35-7)
Recommended Standards
- 3,3''-Dioctyl-2,2':5',2''-terthiophene (CAS 155166-89-5)
- (3β)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-chol-5-en-24-al (CAS 84529-74-8)
- Saflufenacil-N,N-desmethyl (CAS 1246768-30-8)
- Tembotrione-4,6-dihydroxy (CAS 912654-91-2)
- 2,2-Dimethyl-3-((4S)-4-methyltetrahydro-2H-pyran-2-yl)cyclopropane-1-carboxylic acid (CAS 1604687-25-3)
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