2,5-Dichloro-8-(trifluoromethoxy)quinoline CAS 1403765-06-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1403765-06-9
Molecular FormulaC10H4Cl2F3NO
Molecular Weight282.05 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,5-Dichloro-8-(trifluoromethoxy)quinoline CAS 1403765-06-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,5-Dichloro-8-(trifluoromethoxy)quinoline.

2,5-Dichloro-8-(trifluoromethoxy)quinoline (CAS 1403765-06-9) is a high-purity analytical reference standard with the molecular formula C10H4Cl2F3NO and a molecular weight of 282.05 g/mol.

Structurally, 2,5-Dichloro-8-(trifluoromethoxy)quinoline (C10H4Cl2F3NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 282.05 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2,5-Dichloro-8-(trifluoromethoxy)quinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H4Cl2F3NO
Molecular Weight282.05 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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