5,7-Dichloro-4-hydroxy-2-(trifluoromethyl)quinoline CAS 59108-13-3

Purity 97%+In StockPharmaceutical Standards
CAS No.59108-13-3
Molecular FormulaC10H4Cl2F3NO
Molecular Weight282.05 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5,7-Dichloro-4-hydroxy-2-(trifluoromethyl)quinoline CAS 59108-13-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5,7-Dichloro-4-hydroxy-2-(trifluoromethyl)quinoline.

CATO supplies 5,7-Dichloro-4-hydroxy-2-(trifluoromethyl)quinoline (CAS 59108-13-3), a certified reference material (molecular formula C10H4Cl2F3NO, MW 282.05 g/mol) for analytical method development and quality control.

The molecular framework of 5,7-Dichloro-4-hydroxy-2-(trifluoromethyl)quinoline (C10H4Cl2F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5,7-Dichloro-4-hydroxy-2-(trifluoromethyl)quinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H4Cl2F3NO
Molecular Weight282.05 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1973
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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