2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite CAS 1404463-12-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1404463-12-2
Molecular FormulaC46H51FN5O8P
Molecular Weight851.90 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite CAS 1404463-12-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 851.90 g/mol gives 2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite (CAS 1404463-12-2), molecular formula C46H51FN5O8P and molecular weight 851.90 g/mol, is a CATO reference standard with documented purity and traceability.

2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite (C46H51FN5O8P) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC46H51FN5O8P
Molecular Weight851.90 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)23.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF-containing
Nitrogen Atoms5

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