N4-Benzoyl-2-deoxy-5-O-DMT-2-fluoro-cytidine phosphoramidite CAS 161442-19-9
| CAS No. | 161442-19-9 |
| Molecular Formula | C46H51FN5O8P |
| Molecular Weight | 851.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N4-Benzoyl-2-deoxy-5-O-DMT-2-fluoro-cytidine phosphoramidite is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N4-Benzoyl-2-deoxy-5-O-DMT-2-fluoro-cytidine phosphoramidite (CAS 161442-19-9) is a high-purity analytical reference standard with the molecular formula C46H51FN5O8P and a molecular weight of 851.90 g/mol.
The molecular framework of N4-Benzoyl-2-deoxy-5-O-DMT-2-fluoro-cytidine phosphoramidite (C46H51FN5O8P) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N4-Benzoyl-2-deoxy-5-O-DMT-2-fluoro-cytidine phosphoramidite meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C46H51FN5O8P |
| Molecular Weight | 851.90 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 23.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related N Standards
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Recommended Standards
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- 2-Chloro-4,5-difluorobenzoylacetonitrile (CAS 139218-69-2)
- Ethyl 4-(2-ethoxyphenyl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 5611-14-3)
- Tetrazolium Violet (CAS 1719-71-7)
- 3,5-Bis(trifluoromethyl)cyclohexanol (CAS 691410-51-2)
- 3-((2-Chloro-6-fluorobenzyl)thio)-5-(((4-chlorobenzyl)thio)methyl)-4-ethyl-4H-1,2,4-triazole (CAS 344273-89-8)
- 1,8-Dibromo-4,5-dimethoxyanthracene (CAS 1370442-64-0)
- GnRH Associated Peptide (GAP) (1-13), human (CAS 100111-07-7)
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