2-((tert-Butoxycarbonyl)amino)-2-(2,6-dichlorophenyl)acetic acid CAS 1404945-02-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1404945-02-3
Molecular FormulaC13H15Cl2NO4
Molecular Weight320.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-((tert-Butoxycarbonyl)amino)-2-(2,6-dichlorophenyl)acetic acid CAS 1404945-02-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((tert-Butoxycarbonyl)amino)-2-(2,6-dichlorophenyl)acetic acid.

2-((tert-Butoxycarbonyl)amino)-2-(2,6-dichlorophenyl)acetic acid (CAS 1404945-02-3) is a high-purity analytical reference standard with the molecular formula C13H15Cl2NO4 and a molecular weight of 320.17 g/mol.

2-((tert-Butoxycarbonyl)amino)-2-(2,6-dichlorophenyl)acetic acid (C13H15Cl2NO4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H15Cl2NO4
Molecular Weight320.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentCl-containing
Nitrogen Atoms1

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