Glycyrrhizic Acid CAS 1405-86-3
| CAS No. | 1405-86-3 |
| Molecular Formula | C42H62O16 |
| Molecular Weight | 822.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Glycyrrhizic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Glycyrrhizic Acid (CAS 1405-86-3) is a high-purity analytical reference standard with the molecular formula C42H62O16 and a molecular weight of 822.93 g/mol.
The molecular framework of Glycyrrhizic Acid (C42H62O16) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C42H62O16 |
| Molecular Weight | 822.93 g/mol |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Glycyrrhizic Standards
- Glycyrrhizic Acid Impurity 14 (CAS 105038-43-5)
- Glycyrrhizic Acid Impurity 18 (CAS 185805-19-0)
- Glycyrrhizic Acid Impurity 19 (CAS CATO-C4X-253719)
- Glycyrrhizic Acid Impurity 25 (CAS CATO-C4X-253725)
- Glycyrrhizic Acid Impurity 4 (CAS 83896-44-0)
- (18β,20α)-Glycyrrhizic acid (CAS 118441-85-3)
- Glycyrrhizic Acid Impurity 38 (CAS CATO-C4X-253738)
- Glycyrrhizic Acid-d3 (CAS CATO-C4X-25371)
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