Glycyrrhizic Acid Impurity 18 CAS 185805-19-0
| CAS No. | 185805-19-0 |
| Molecular Formula | C42H62O16 |
| Molecular Weight | 822.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Glycyrrhizic Acid Impurity 18 (CAS 185805-19-0, C42H62O16) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Glycyrrhizic Acid Impurity 18 (C42H62O16) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 822.93 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Glycyrrhizic Acid Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C42H62O16 |
| Molecular Weight | 822.93 g/mol |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
Related Glycyrrhizic Standards
- Glycyrrhizic Acid Impurity 14 (CAS 105038-43-5)
- Glycyrrhizic Acid Impurity 19 (CAS CATO-C4X-253719)
- Glycyrrhizic Acid Impurity 25 (CAS CATO-C4X-253725)
- Glycyrrhizic Acid Impurity 4 (CAS 83896-44-0)
- Glycyrrhizic Acid (CAS 1405-86-3)
- (18β,20α)-Glycyrrhizic acid (CAS 118441-85-3)
- Glycyrrhizic Acid Impurity 38 (CAS CATO-C4X-253738)
- Glycyrrhizic Acid-d3 (CAS CATO-C4X-25371)
Recommended Standards
- (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(6-((1-(dimethylamino)ethylidene)amino)-7H-purin-7-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite (CAS 220252-91-5)
- 6-((6-Carboxy-2-((11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl)oxy)-4,5-dihydroxytetrahydro-2h-pyran-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2h-pyran-2-carboxylic acid (CAS 1970133-70-0)
- Licoricesaponin K2 (CAS 135815-61-1)
- Glycyrrhizin (CAS 103000-77-7)
- Lincomycin Impurity 10 (CAS CATO-C4X-134210)
- Prednisolone Impurity 16 (CAS CATO-C4X-173716)
- Regorafenib Impurity 48 (CAS CATO-C4X-104748)
- 5-Acetyl-2-thienylboronic Acid (CAS 206551-43-1)
- 2-Amino-5,6,7,8-tetrahydro-3H-pyrimido[4,5-b]indol-4(9H)-one (CAS 188062-45-5)
- 1-(2-Chlorophenyl)-3-[4-(trifluoromethoxy)phenyl]urea (CAS 406930-04-9)
- 4-Bromo-1-fluoro-2-methylnaphthalene (CAS 37113-05-6)
- 1-(1-Isopropyl-1h-benzo[d]imidazol-2-yl)ethan-1-amine (CAS 947013-92-5)
- 4-(tert-Butyl)phthalamide (CAS 52319-96-7)
- Tau Peptide (298-312) trifluoroacetate salt (CAS 330456-47-8)
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