Dapagliflozin Impurity 49 CAS 1408077-50-8
| CAS No. | 1408077-50-8 |
| Molecular Formula | C15H15ClO2 |
| Molecular Weight | 262.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Dapagliflozin Impurity 49 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Dapagliflozin Impurity 49 (CAS 1408077-50-8), a pharmacopoeial impurity reference standard (molecular formula C15H15ClO2, MW 262.73 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C15H15ClO2, Dapagliflozin Impurity 49 contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 262.73 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C15H15ClO2 |
| Molecular Weight | 262.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
Related Dapagliflozin Standards
- Dapagliflozin Impurity 93 (CAS 525561-43-7)
- Dapagliflozin Impurity 74 (CAS 5032-11-1)
- Dapagliflozin Impurity 204 (CAS CATO-C4X-1138204)
- Dapagliflozin Impurity N50 (CAS 21900-52-7)
- Dapagliflozin Impurity 102 (CAS CATO-C4X-1138102)
- Dapagliflozin Impurity 55 (CAS CATO-C4X-113855)
- Dapagliflozin Impurity 8 (CAS 1662702-90-0)
- Dapagliflozin Impurity N15 (CAS 610-71-9)
Recommended Standards
- Tert-butyl 3-(2-chloroacetamido)pyrrolidine-1-carboxylate (CAS 865432-10-6)
- 3-Chlorobisphenol A (CAS 74192-35-1)
- Tert-butyl (R)-4-(chlorocarbonyl)-3-methylpiperazine-1-carboxylate (CAS 438050-54-5)
- 1-(1-(3-Chlorophenyl)-1h-imidazol-2-yl)piperazine (CAS 1019115-41-3)
- Tegoprazan Impurity N18 (CAS 1640981-16-3)
- Orforglipron Impurity 16 (CAS CATO-C4X-323416)
- Fluzoparib Impurity 3 (CAS CATO-C4X-32523)
- 3-Oxo-2,3-dihydroisoxazole-4-carboxylic acid (CAS 178316-78-4)
- (2S)-2-tert-Butoxycarbonylamino-pent-4-enoic acid ethyl ester (CAS 1028191-70-9)
- 3-Ethylpiperidine-3-carboxylic acid hydrochloride (CAS 116140-23-9)
- [1S-[1α(R),3α(Z)]]-3-(2-Chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylic Acid Cyano(3-phenoxyphenyl)methyl Ester(Cyhalothrin Isomer) (CAS 76703-64-5)
- 1-Bromo-3-propoxycyclobutane (CAS 1516177-37-9)
- 3-(5-methyl-1,3-thiazol-2-yl)piperidine (CAS 1248102-35-3)
- Liraglutide Impurity 31 (CAS CATO-C4X-199231)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com