1-[3-(trifluoromethyl)phenyl]imidazolidin-2-one CAS 14088-95-0
| CAS No. | 14088-95-0 |
| Molecular Formula | C10H9F3N2O |
| Molecular Weight | 230.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-[3-(trifluoromethyl)phenyl]imidazolidin-2-one.
1-[3-(trifluoromethyl)phenyl]imidazolidin-2-one (CAS 14088-95-0), molecular formula C10H9F3N2O and molecular weight 230.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-[3-(trifluoromethyl)phenyl]imidazolidin-2-one (C10H9F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9F3N2O |
| Molecular Weight | 230.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related trifluoromethyl Standards
- 2-(2-(Trifluoromethyl)-1H-benzo[d]imidazol-1-yl)ethan-1-ol (CAS 116040-98-3)
- [1-methyl-5-(trifluoromethyl)-1h-1,3-benzodiazol-2-yl]methanol (CAS 1243735-94-5)
- 1-[2-(trifluoromethyl)phenyl]imidazolidin-2-one (CAS 1550068-19-3)
- 1-(4-(Trifluoromethyl)phenyl)imidazolidin-2-one (CAS 162748-21-2)
- 1-(6-(Trifluoromethyl)-3H-imidazo[4,5-b]pyridin-2-yl)ethanamine (CAS 1707727-62-5)
- 1-Methyl-7-(trifluoromethyl)-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 1783769-47-0)
- 5-Methyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 827589-02-6)
- 8-(Trifluoromethyl)-1,3,4,5-tetrahydro-2H-benzo[b][1,4]diazepin-2-one (CAS 37040-48-5)
Recommended Standards
- 1-(4-Amino-2,3-dihydro-1h-indol-1-yl)-2,2,2-trifluoroethan-1-one (CAS 1368864-43-0)
- (S)-4-Methyl-2-(4-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole (CAS 1416820-33-1)
- 1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (CAS 136675-88-2)
- (3-Aminoazetidin-1-yl)(2,3,4-trifluorophenyl)methanone (CAS 1511446-12-0)
- 2-Amino-4-chloro-N-(2-methylquinolin-6-yl)benzamide (CAS 832102-29-1)
- Dimethyl (3-(4-fluorophenoxy)-2-oxopropyl)phosphonate (CAS 55444-94-5)
- Ethyl 2-oxo-2-(1-tosyl-1H-pyrrol-2-yl)acetate (CAS 69551-49-1)
- 2-Methyl-5-morpholinoaniline (CAS 1007211-91-7)
- (R)-3-((tert-Butoxycarbonyl)amino)-3-(3,4-dimethoxyphenyl)propanoic acid (CAS 500788-93-2)
- 2-((Trimethylsilyl)oxy)pyrimidin-4-amine (CAS 56653-26-0)
- Cefoxitin EP Impurity C（Cefalotin EP Impurity D） (CAS 10590-10-0)
- 6-(2,5-Dioxotetrahydrofuran-3-yl)-4-methyltetrahydro-1H-furo[3,4-c]pyran-1,3(6H)-dione (CAS 26427-28-1)
- trans-2-[2-(4-Bromophenyl)-2-oxoethyl]cyclohexane-1-carboxylic acid (CAS 735274-88-1)
- (D-Trp32)-Neuropeptide Y (porcine) trifluoroacetate salt (CAS 153549-78-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com