Ethyl 5-(phenylamino)thiazole-4-carboxylate CAS 1410092-36-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1410092-36-2
Molecular FormulaC12H12N2O2S
Molecular Weight248.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 5-(phenylamino)thiazole-4-carboxylate CAS 1410092-36-2 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Ethyl 5-(phenylamino)thiazole-4-carboxylate (CAS 1410092-36-2) is a high-purity analytical reference standard with the molecular formula C12H12N2O2S and a molecular weight of 248.30 g/mol.

The molecular framework of Ethyl 5-(phenylamino)thiazole-4-carboxylate (C12H12N2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), Ethyl 5-(phenylamino)thiazole-4-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H12N2O2S
Molecular Weight248.30 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Nitrogen Atoms2
Sulfur Atoms1

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