Dapagliflozin Impurity 85 CAS 2452300-79-5
| CAS No. | 2452300-79-5 |
| Molecular Formula | C42H48Cl2O12 |
| Molecular Weight | 815.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Dapagliflozin Impurity 85 (CAS 2452300-79-5) is a certified pharmaceutical impurity reference standard with the molecular formula C42H48Cl2O12 and a molecular weight of 815.73 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system, Dapagliflozin Impurity 85 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 815.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Dapagliflozin Impurity 85 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C42H48Cl2O12 |
| Molecular Weight | 815.73 g/mol |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
Related Dapagliflozin Standards
- Dapagliflozin Impurity 124 (CAS 2714814-62-5)
- Dapagliflozin Impurity 162 (CAS CATO-C4X-1138162)
- Dapagliflozin Impurity 170 (CAS CATO-C4X-1138170)
- Dapagliflozin impurity 221 (CAS CATO-C4X-1138221)
- Dapagliflozin Impurity 3 (CAS CATO-C4X-11383)
- Dapagliflozin Impurity 71 (CAS CATO-C4X-113871)
- Dapagliflozin Impurity 112 (CAS CATO-C4X-1138112)
- Dapagliflozin Impurity 192 (CAS CATO-C4X-1138192)
Recommended Standards
- N1,N1'-(1,3-phenylene)bis(2-chloro-N1,N3,N3-triphenylbenzene-1,3-diamine) (CAS 1800321-80-5)
- 680571-51-1 Kigamicin C (CAS 680571-51-1)
- (S)-1-(6-Benzamido-9H-purin-9-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propan-2-yl (2-cyanoethyl) diisopropylphosphoramidite (CAS 851050-24-3)
- (4-Chlorophenyl)trihexadecylsilane (CAS 18822-35-0)
- Niraparib Impurity 10 (CAS 2091464-38-7)
- Osimertinib Impurity 95 (CAS CATO-C4X-204595)
- Fluticasone Impurity 21 (CAS 397864-40-3)
- (Z)-N,N-Dimethyl-3-phenylacrylamide (CAS 131214-20-5)
- Tert-butyl (3-hydroxy-1-oxaspiro[3.3]Heptan-6-yl)carbamate (CAS 2306261-37-8)
- Ethyl 2-phenyl-6-(trifluoromethyl)nicotinate (CAS 149770-27-4)
- 4-Chloro-6-(2-fluoropropan-2-yl)-1,3,5-triazin-2-amine (CAS 252577-14-3)
- tert-Butyl (trans-2-cyanocyclohexyl)carbamate (CAS 824950-16-5)
- 1-Ethyl-3-isopropylbenzene (CAS 4920-99-4)
- Des-[Ser]8-Liraglutide (CAS CATO-C4X-199233)
Why CATO?
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