Clopidogrel Impurity 27 CAS 141109-18-4
| CAS No. | 141109-18-4 |
| Molecular Formula | C15H16ClNO2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Clopidogrel Impurity 27 (CAS 141109-18-4), a pharmacopoeial impurity reference standard (molecular formula C15H16ClNO2SHCl, MW 346.27 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Clopidogrel Impurity 27 (C15H16ClNO2SHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 346.27 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C15H16ClNO2S HCl |
| Molecular Weight | 346.27 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Clopidogrel Standards
- Clopidogrel Impurity 74 (CAS 1008008-56-7)
- Clopidogrel Impurity 82 (CAS 1015247-87-6)
- rac-Clopidogrel EP Impurity A HCl (CAS 1015247-88-7)
- rac Clopidogrel [(tert-Butylcarbonyl)oxy]methyl ester (CAS 1043913-82-1)
- 2-Oxo Clopidogrel (Mixture of Diastereomers) (CAS 109904-27-0)
- Clopidogrel Impurity 42 (CAS 109904-36-1)
- cis-Clopidogrel glutathione disulfide, mixture of diastereomers (CAS 1118605-95-0)
- Clopidogrel Impurity 48 (CAS 111954-31-5)
Recommended Standards
- Osimertinib Impurity 10 (CAS 1421373-98-9)
- Dequalinium impurity 27 (CAS CATO-C4X-193627)
- chondroitin sulfate impurity A (CAS CATO-C4X-32811)
- Diethyl (5-(2-isopentyl-1,3-dithian-2-yl)furan-2-yl)phosphonate (CAS 1199589-68-8)
- 5-Neopentylpyrimidin-2-amine (CAS 42088-86-8)
- 4-Chloro-5H-indeno[1,2-d]pyrimidine (CAS 197861-27-1)
- 5-((4-Bromophenyl)sulfonyl)-N-methyl-1,2,3-thiadiazole-4-carboxamide (CAS 339107-83-4)
- 6-(Methylsulfonyl)-3-nitroimidazo[1,2-b]pyridazine (CAS 56023-65-5)
- (2R,3R,4R,5S,6R)-2-((benzoyloxy)methyl)-5-hydroxy-6-(p-tolylthio)tetrahydro-2H-pyran-3,4-diyl dibenzoate (CAS 1882063-03-7)
- Peptide Impurity (CAS CATO-CPTD788810)
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