Ritonavir EP Impurity R CAS 1414933-80-4
| CAS No. | 1414933-80-4 |
| Molecular Formula | C37H48N6O5S2 |
| Molecular Weight | 720.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Ritonavir EP Impurity R is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 720.94 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Ritonavir EP Impurity R (CAS 1414933-80-4), a pharmacopoeial impurity reference standard (molecular formula C37H48N6O5S2, MW 720.94 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C37H48N6O5S2 |
| Molecular Weight | 720.94 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
Related Ritonavir Standards
- Ritonavir (CAS 155213-67-5)
- Ritonavir Geo-isomer (CAS 959315-21-0)
- Ritonavir EP Impurity N (CAS 202816-62-4)
- Ritonavir EP Impurity O (CAS 1414933-81-5)
- Ritonavir EP Impurity Q (CAS 1414933-82-6)
- Ritonavir impurity 48 (CAS CATO-C4X-175148)
- Ritonavir Impurity 56 (CAS CATO-C4X-175156)
- Ritonavir Dehydro (CAS 1156504-13-0)
Recommended Standards
- Nonacyclo[43.3.1.13,7.19,13.115,19.121,25.127,31.133,37.139,43]hexapentaconta-1(49),3,5,7(56),9,11,13(55),15,17,19(54),21,23,25(53),27,29,31(52),33,35,37(51),39,41,43(50),45,47-tetracosaene (CAS 82040-66-2)
- O-(2-(1,2-Dihexanoyl-3-(7-oxo-11-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)undecanoyl)triazyl)ethyl) methanesulfonothioate (CAS 1322625-00-2)
- 799812-76-3 (2R)-2,3-Bis(hexadecanoyloxy)propyl 3,4,5-trihydroxybenzoate DTXSID70677182 (CAS 799812-76-3)
- N1-(1-Benzyl-3-hydroxy-5-phenyl-4-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}pentyl)-N2-{[[(5-isopropyl-1,3-thiazol-2-yl)methyl](methyl)amino]carbonyl}valinamide (CAS 2096495-89-3)
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- 4-(1-Boc-4-piperidyl)benzoic Acid (CAS 149353-75-3)
- 3-(3-Amino-1h-1,2,4-triazol-1-yl)-1-methylpyrrolidin-2-one (CAS 1339393-63-3)
- CAS 1628530-42-6 (CAS 1628530-42-6)
- Gatifloxacin USP RC E (CAS 1029364-65-5)
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- Ethyl cis-4-Aminocyclohexanecarboxylate Hydrochloride (CAS 61367-17-7)
- Semaglutide impurity 277 (CAS CATO-C4X-2226277)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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