Ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate CAS 141573-95-7
| CAS No. | 141573-95-7 |
| Molecular Formula | C8H10F2N2O2 |
| Molecular Weight | 204.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 204.17 g/mol gives Ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate (CAS 141573-95-7), molecular formula C8H10F2N2O2 and molecular weight 204.17 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 204.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H10F2N2O2 |
| Molecular Weight | 204.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- 1-(Difluoromethyl)-4-iodo-1H-pyrazole (CAS 1041205-43-9)
- 2-[1-(difluoromethyl)-3,5-dimethyl-1h-pyrazol-4-yl]acetic acid (CAS 1221724-52-2)
- Ethyl 1-(difluoromethyl)-3-methyl-1H-pyrazole-5-carboxylate (CAS 128537-24-6)
- 5-(difluoromethyl)-1-ethyl-3-methyl-1H-pyrazole-4-carboxylic acid (CAS 1384427-73-9)
- Ethyl 5-(difluoromethyl)-1-methyl-1H-pyrazole-3-carboxylate (CAS 1437312-22-5)
- Methyl 5-(difluoromethyl)-1-ethyl-1H-pyrazole-4-carboxylate (CAS 1443287-95-3)
- 5-(Difluoromethyl)-3,4-dimethoxypyridin-2-amine (CAS 1804451-51-1)
- 2-(Difluoromethyl)-3,5-dimethoxypyridin-4-amine (CAS 1805159-03-8)
Recommended Standards
- 2-((3,3,3-Trifluoropropyl)sulfinyl)acetic acid (CAS 1408206-32-5)
- 1,1,1-Trifluoro-4-(methylsulfonyl)butan-2-one (CAS 1343593-04-3)
- 1-((Trifluoromethyl)sulfonyl)azetidin-3-amine (CAS 1449278-62-9)
- Ethyl 2,2-difluoro-2-(1-methyl-1h-pyrazol-5-yl)acetate (CAS 1343190-46-4)
- n-Cyclopentyl-2-methylaniline (CAS 503426-96-8)
- 1,3,6-Trimethyl-5-((thiophen-2-ylmethyl)amino)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione (CAS 941954-71-8)
- 2-Methyl-6-nitro-1,2,3,4-tetrahydroisoquinolin-7-amine (CAS 911300-58-8)
- 4-(Difluoromethyl)-2-(ethylsulfonyl)-6-(4-fluorophenyl)pyrimidine (CAS 832739-68-1)
- 1-(3-Chlorobenzyl)-1H-pyrazol-4-ol (CAS 1593233-73-8)
- 3-Amino-6-benzyl-N-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 723748-21-8)
- 3,4,5-Tribromo-1-(4-nitrophenyl)-1H-pyrazole (CAS 175135-29-2)
- 2-Ethoxy-4-((trimethylsilyl)oxy)pyrimidine (CAS 171109-23-2)
- 5-Hydrazinyl-6-(methylthio)-1,2,4-triazin-3(2H)-one (CAS 31697-24-2)
- Allo-Thr5-Tirzepatide (CAS CATO-CPTD788934)
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