4-Chloro-1-(3-fluoro-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine CAS 1416341-19-9
| CAS No. | 1416341-19-9 |
| Molecular Formula | C12H8ClFN4 |
| Molecular Weight | 262.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 4-Chloro-1-(3-fluoro-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 262.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 4-Chloro-1-(3-fluoro-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 1416341-19-9), a certified reference material (molecular formula C12H8ClFN4, MW 262.67 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8ClFN4 |
| Molecular Weight | 262.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 6-Chloro-9-(2-fluorobenzyl)-9h-purine (CAS 101155-08-2)
- 4-chloro-1-(4-fluorophenyl)-6-methyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 1097095-32-3)
- 4-Chloro-1-(3-fluorophenyl)-6-methyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 1269705-39-6)
- N-(3-Chloro-4-fluorophenyl)-1H-pyrazolo[4,3-b]pyridin-3-amine (CAS 1330624-42-4)
- 6-Chloro-2-(4-fluoro-1H-indol-2-yl)pyridin-3-ol (CAS 1426942-84-8)
- 2-(2-Chloro-4-fluorophenyl)benzo[d]oxazol-5-amine (CAS 313527-40-1)
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- 6-Chloro-3-oxo-3,4-dihydro-2h-1,4-benzoxazine-7-sulfonamide (CAS 3656-85-7)
Recommended Standards
- 4-(((6-Chloropyridin-2-yl)oxy)methyl)-3-fluorobenzonitrile (CAS 2230200-58-3)
- 6-(Tert-butyl)-2-chloro-4-(trifluoromethyl)nicotinonitrile (CAS 914208-21-2)
- 2,2-difluoro-2H-1,3-benzodioxole-5-sulfonyl chloride (CAS 313681-67-3)
- 6-Chloro-5-methoxy-2H-benzo[e][1,2,4]thiadiazin-3(4H)-one 1,1-dioxide (CAS 2100839-44-7)
- 4-(1-Bromoethyl)-6-[(4-chlorophenyl)thio]-5-fluoropyrimidine (CAS 1112937-26-4)
- 3-Ethyl-2-(2,4,4-trimethylpentyl)pyrrolidine (CAS 525537-82-0)
- (3-Butylphenyl)boronic acid (CAS 743437-84-5)
- 2-(4-Bromophenyl)-2-oxoacetaldehyde (CAS 5195-29-9)
- Cephalexin Impurity 18 (CAS 1260607-12-2)
- Milbemycin A4 Oxime (CAS 93074-04-5)
- Rel-benzyl ((1r,4r)-4-(bromomethyl)cyclohexyl)carbamate (CAS 2205415-17-2)
- 1-(3-Bromobenzoyl)-3-methylpiperazine (CAS 1240567-90-1)
- 2-(1-Isopropyl-4-methyl-3-oxo-2-piperazinyl)-acetic acid (CAS 1236267-00-7)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
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