2-(5-Amino-3-(2-fluorophenyl)-1H-pyrazol-1-yl)-6-methylpyrimidin-4(3H)-one CAS 1416342-10-3
| CAS No. | 1416342-10-3 |
| Molecular Formula | C14H12FN5O |
| Molecular Weight | 285.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-(5-Amino-3-(2-fluorophenyl)-1H-pyrazol-1-yl)-6-methylpyrimidin-4(3H)-one (CAS 1416342-10-3), a certified reference material (molecular formula C14H12FN5O, MW 285.28 g/mol) for analytical method development and quality control.
2-(5-Amino-3-(2-fluorophenyl)-1H-pyrazol-1-yl)-6-methylpyrimidin-4(3H)-one (C14H12FN5O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H12FN5O |
| Molecular Weight | 285.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Amino Standards
- 2-(5-Amino-3-(4-fluorophenyl)-1H-pyrazol-1-yl)-6-methylpyrimidin-4(3H)-one (CAS 1416346-85-4)
- (3-Amino-5-methoxybenzofuran-2-yl)(4-fluorophenyl)methanone (CAS 182124-33-0)
- (7-Amino-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(4-methoxyphenyl)methanone (CAS 767316-04-1)
- 7-Amino-1-[4-hydroxy-3-(hydroxymethyl)butyl]-1,3,6,8-tetrazaspiro[4.4]non-6-ene-2,4,9-trione (CAS 1379017-92-1)
- 2-Amino-6-ethyl-7-hydroxy-3-(5-methyl-1h-imidazol-2-yl)-4h-chromen-4-one (CAS 1092333-30-6)
- 2-[5-Amino-3-(2-furyl)-1H-pyrazol-1-yl]-6-isopropylpyrimidin-4(3H)-one (CAS 1206993-21-6)
- 2-[5-Amino-3-(2-furyl)-1H-pyrazol-1-yl]-6-propylpyrimidin-4(3H)-one (CAS 1207000-54-1)
- 2-(5-Amino-3-(furan-2-yl)-1H-pyrazol-1-yl)-5-ethyl-6-methylpyrimidin-4(3H)-one (CAS 1207025-93-1)
Recommended Standards
- (S)-3-(4-fluorophenyl)-5-(4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-6-yl)-1,2,4-oxadiazole (CAS 1263033-60-8)
- N-(3-Cyanothiophen-2-yl)-5-(furan-2-yl)isoxazole-3-carboxamide (CAS 1251708-25-4)
- 1-(4-Fluorophenyl)-3-(2-methylpyrazolo[1,5-a]pyrimidin-6-yl)urea (CAS 1795190-98-5)
- 1-(5-(4-(Trifluoromethyl)phenyl)thiophen-2-yl)ethan-1-one oxime (CAS 1114824-10-0)
- 2-(2-(4-Methylbenzoyl)hydrazine-1-carbonyl)benzoic acid (CAS 118071-17-3)
- 2-(6-(tert-Butyl)-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-chlorobenzyl acetate (CAS 1242157-24-9)
- H-Gly-Pro-Leu-bNA . HCl (K-1340.0250) (CAS 100929-83-7)
- 3-Phenylbut-2-enenitrile (CAS 14799-79-2)
- tert-Butyl [1,1'-biphenyl]-2-ylcarbamate (CAS 138344-50-0)
- n-(5-Bromopyridin-2-yl)-2-(methylamino)acetamide hydrochloride (CAS 1240528-42-0)
- Aprepitant Impurity 17 (CAS 1333998-27-8)
- Benzyl 4-(2-fluoropyridin-3-yl)-4-hydroxypiperidine-1-carboxylate (CAS 161610-13-5)
- (2E)-3-[4-(benzyloxy)phenyl]prop-2-enoic acid 3-[4-(Benzyloxy)phenyl]acrylic acid 3-[4-(Benzyloxy)phenyl]prop-2-enoic acid 6272-45-3 (CAS 6272-45-3)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
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